|
Symbol Name ID |
Irf6
interferon regulatory factor 6 MGI:1859211 |
| Darker colors indicate more annotations |
| Human Phenotypes | Micrognathia |
Fibrous syngnathia |
Hypoplasia of the maxilla |
Short neck |
Ulnar bowing |
Clinodactyly of the 5th finger |
Camptodactyly of finger |
Short phalanx of finger |
Symphalangism affecting the phalanges of the hand |
Absent thumb |
Short thumb |
Postaxial foot polydactyly |
Preaxial foot polydactyly |
Sandal gap |
Toe syndactyly |
2-3 toe syndactyly |
Oligodactyly |
Mesoaxial polydactyly |
Syndactyly |
Cutaneous finger syndactyly |
Finger syndactyly |
3-4 finger syndactyly |
Short foot |
Absent radius |
Abnormal metacarpal morphology |
Short metacarpal |
Short palm |
Split hand |
Limb undergrowth |
Pterygium |
Axillary pterygium |
Intercrural pterygium |
Popliteal pterygium |
Flexion contracture |
Arthrogryposis multiplex congenita |
Joint stiffness |
Hypoplastic iliac wing |
Abnormal rib morphology |
Hypoplastic scapulae |
Scoliosis |
| Disease(s) Associated with IRF6 | ||||||||||||||||||||||||||||||||||||||||
| popliteal pterygium syndrome | ||||||||||||||||||||||||||||||||||||||||
| syndactyly |
| Mouse Phenotypes | abnormal craniofacial bone morphology |
abnormal cranium morphology |
absent presphenoid bone |
abnormal jaw morphology |
abnormal tooth morphology |
taurodontia |
abnormal incisor morphology |
abnormal incisor color |
abnormal molar morphology |
abnormal molar crown morphology |
abnormal molar cusp morphology |
abnormal molar root morphology |
decreased molar number |
abnormal tooth development |
abnormal enamel development |
abnormal ameloblast morphology |
abnormal enamel mineralization |
abnormal enamel morphology |
abnormal enamel rod pattern |
reduced enamel thickness |
supernumerary teeth |
abnormal Hertwig epithelial root sheath morphology |
abnormal mandibular angle morphology |
small mandible |
abnormal palatine bone horizontal plate morphology |
abnormal phalanx morphology |
fused phalanges |
abnormal skeleton morphology |
decreased length of long bones |
split xiphoid process |
short sternum |
small vertebrae |
synostosis |
delayed bone ossification |
|
| Availability | Mouse Genotype | ||||||||||||||||||||||||||||||||||
| Irf6clft1/Irf6clft1 | |||||||||||||||||||||||||||||||||||
| Irf6Gt(OST398253)Lex/Irf6Gt(OST398253)Lex | |||||||||||||||||||||||||||||||||||
| Irf6tm1Mjd/Irf6tm1Mjd | |||||||||||||||||||||||||||||||||||
| Irf6tm1Bcsl/Irf6tm1Bcsl Pitx2tm4(cre)Jfm/Pitx2+ (conditional) |
|||||||||||||||||||||||||||||||||||
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
||
|
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support. |
last database update 04/09/2024 MGI 6.23 |
|
|
|
||
Analysis Tools