|
Symbol Name ID |
Ror2
receptor tyrosine kinase-like orphan receptor 2 MGI:1347521 |
| Darker colors indicate more annotations |
| Human Phenotypes | Frontal bossing |
Micrognathia |
Retrognathia |
Malar flattening |
Macrocephaly |
Delayed cranial suture closure |
Wide anterior fontanel |
Flat face |
Midface retrusion |
Prominent forehead |
Long philtrum |
Short philtrum |
Exaggerated cupid's bow |
Tented upper lip vermilion |
Thin upper lip vermilion |
Ankyloglossia |
Gingival overgrowth |
Abnormal palate morphology |
Absent uvula |
Bifid tongue |
Macroglossia |
Downturned corners of mouth |
Triangular mouth |
Wide mouth |
Abnormality of the dentition |
Supernumerary tooth |
Hypodontia |
Delayed eruption of permanent teeth |
Dental crowding |
Open bite |
Orofacial cleft |
Anteverted nares |
Depressed nasal bridge |
Wide nasal bridge |
Short nose |
Long eyelashes |
Long palpebral fissure |
Downslanted palpebral fissures |
Upslanted palpebral fissure |
Epicanthus |
| Disease(s) Associated with ROR2 | ||||||||||||||||||||||||||||||||||||||||
| autosomal recessive Robinow syndrome | ||||||||||||||||||||||||||||||||||||||||
| brachydactyly type B1 |
| Mouse Phenotypes | abnormal craniofacial morphology |
abnormal cranium morphology |
abnormal Meckel's cartilage morphology |
short Meckel's cartilage |
increased cranium width |
large orbits |
abnormal jaw morphology |
abnormal mandible morphology |
abnormal mandibular angle morphology |
abnormal mandibular condyloid process morphology |
short mandible |
abnormal maxilla morphology |
abnormal nasal bone morphology |
broad nasal bone |
short nasal bone |
abnormal middle ear ossicle morphology |
abnormal malleus morphology |
abnormal craniofacial development |
abnormal nasal capsule morphology |
failure of palatal shelf elevation |
abnormal facial morphology |
midface hypoplasia |
cleft secondary palate |
cleft palate |
short snout |
|
| Availability | Mouse Genotype | |||||||||||||||||||||||||
| Ror2em1(IMPC)Mbp/Ror2em1(IMPC)Mbp | ||||||||||||||||||||||||||
| Ror2tm1.2Meg/Ror2tm1.2Meg | ||||||||||||||||||||||||||
| Ror2tm1Anec/Ror2tm1Anec | ||||||||||||||||||||||||||
| Ror2tm1Gdy/Ror2tm1Gdy | ||||||||||||||||||||||||||
| Ror2tm1Ymi/Ror2tm1Ymi | ||||||||||||||||||||||||||
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/16/2024 MGI 6.23 |
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