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Symbol
Name
ID
Mapk1
mitogen-activated protein kinase 1
MGI:1346858
Phenotype annotations related to muscle
Darker colors indicate more annotations
Human Phenotypes
Generalized hypotonia
Disease(s) Associated with MAPK1
Noonan syndrome 13

Mouse Phenotypes
thin myocardium
decreased cardiac muscle contractility
increased cardiomyocyte apoptosis
abnormal tongue muscle morphology
abnormal extrinsic tongue muscle morphology
Availability Mouse Genotype
Mapk1tm1Moga/Mapk1tm1Moga
Mapk1tm1Melo/Mapk1+
Mapk1tm1Gela/Mapk1tm1Gela
H2az2Tg(Wnt1-cre)11Rth/H2az2+  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/09/2024
MGI 6.23
The Jackson Laboratory