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Symbol
Name
ID
Fyb1
FYN binding protein 1
MGI:1346327
Phenotype annotations related to hematopoietic system
Darker colors indicate more annotations
Human Phenotypes
Increased circulating IgA concentration
Increased circulating IgE concentration
Abnormal bleeding
Epistaxis
Gingival bleeding
Joint hemorrhage
Menorrhagia
Persistent bleeding after trauma
Prolonged bleeding time
Bruising susceptibility
Purpura
Petechiae
Spontaneous hematomas
Abnormal megakaryocyte morphology
Increased megakaryocyte colony forming unit count
Megakaryocytopenia
Anemia of inadequate production
Poikilocytosis
Acanthocytosis
Increased total leukocyte count
Thrombocytopenia
Congenital thrombocytopenia
Intermittent thrombocytopenia
Abnormal platelet shape
Abnormal platelet volume
Decreased mean platelet volume
Splenomegaly
Disease(s) Associated with FYB1
thrombocytopenia

Mouse Phenotypes
abnormal leukocyte adhesion
decreased T cell proliferation
decreased thymocyte number
thrombocytopenia
abnormal T cell physiology
Availability Mouse Genotype
Fyb1tm1b(EUCOMM)Hmgu/Fyb1tm1b(EUCOMM)Hmgu
Fyb1tm1Gak/Fyb1tm1Gak

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory