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Symbol
Name
ID
Msh6
mutS homolog 6
MGI:1343961
Phenotype annotations related to digestive/alimentary system
Darker colors indicate more annotations
Human Phenotypes
Gastrointestinal hemorrhage
Neoplasm of the rectum
Adenocarcinoma of the colon
Hereditary nonpolyposis colorectal carcinoma
Adenomatous colonic polyposis
Colon cancer
Intestinal polyposis
Neoplasm of the stomach
Constipation
Nausea and vomiting
Neoplasm of the liver
Hepatocellular carcinoma
Adenocarcinoma of the small intestine
Disease(s) Associated with MSH6
hereditary nonpolyposis colorectal cancer type 5
Lynch syndrome
mismatch repair cancer syndrome

Mouse Phenotypes
increased intestinal adenoma incidence
increased gastrointestinal tumor incidence
Availability Mouse Genotype
Msh6tm1Htr/Msh6tm1Htr
Msh6tm1Rak/Msh6tm1Rak
Msh6tm1Wed/Msh6tm1Wed

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/18/2025
MGI 6.24
The Jackson Laboratory