Symbol Name ID |
Xrcc4
X-ray repair complementing defective repair in Chinese hamster cells 4 MGI:1333799 |
Darker colors indicate more annotations |
Human Phenotypes | Increased circulating IgA level |
Increased circulating IgG level |
Decreased circulating antibody level |
Paraproteinemia |
Disease(s) Associated with XRCC4 | ||||
multiple myeloma |
Mouse Phenotypes | abnormal cell physiology |
increased cellular sensitivity to gamma-irradiation |
increased neuron apoptosis |
abnormal DNA repair |
spontaneous chromosome breakage |
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Availability | Mouse Genotype | |||||
Xrcc4tm1Fwa/Xrcc4tm1Fwa | ||||||
Tg(Cr2-cre)3Cgn/? Xrcc4tm1Fwa/Xrcc4tm2Fwa (conditional) |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/09/2024 MGI 6.23 |
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