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Symbol
Name
ID
Xrcc4
X-ray repair complementing defective repair in Chinese hamster cells 4
MGI:1333799
Phenotype annotations related to cellular
Darker colors indicate more annotations
Human Phenotypes
Increased circulating IgA level
Increased circulating IgG level
Decreased circulating antibody level
Paraproteinemia
Disease(s) Associated with XRCC4
multiple myeloma

Mouse Phenotypes
abnormal cell physiology
increased cellular sensitivity to gamma-irradiation
increased neuron apoptosis
abnormal DNA repair
spontaneous chromosome breakage
Availability Mouse Genotype
Xrcc4tm1Fwa/Xrcc4tm1Fwa
Tg(Cr2-cre)3Cgn/?
Xrcc4tm1Fwa/Xrcc4tm2Fwa  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/09/2024
MGI 6.23
The Jackson Laboratory