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Symbol
Name
ID

Mapk8ip1
mitogen-activated protein kinase 8 interacting protein 1
MGI:1309464

Phenotype annotations related to homeostasis/metabolism

*	Aspects of the system are reported to show a normal phenotype.
	Darker colors indicate more annotations

Human Phenotypes	Type II diabetes mellitus	Insulin resistance
Disease(s) Associated with MAPK8IP1	Type II diabetes mellitus	Insulin resistance
type 2 diabetes mellitus

Mouse Phenotypes		homeostasis/metabolism phenotype	decreased susceptibility to neuronal excitotoxicity	decreased circulating leptin level	decreased respiratory quotient	abnormal gluconeogenesis	increased insulin sensitivity	decreased liver triglyceride level	decreased susceptibility to ischemic brain injury
Availability	Mouse Genotype	homeostasis/metabolism phenotype	decreased susceptibility to neuronal excitotoxicity	decreased circulating leptin level	decreased respiratory quotient	abnormal gluconeogenesis	increased insulin sensitivity	decreased liver triglyceride level	decreased susceptibility to ischemic brain injury
	Mapk8ip1^tm1Plhn/Mapk8ip1^tm1Plhn
	Mapk8ip1^tm1Rjd/Mapk8ip1^tm1Rjd	*
	Mapk8ip1^tm2.1Rjd/Mapk8ip1^tm2.1Rjd	*
	Mapk8ip1^tm3.1Rjd/Mapk8ip1^tm3.1Rjd
	Mapk8ip1^tm1Wae/Mapk8ip1⁺	*

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 03/31/2026 MGI 6.24