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Symbol
Name
ID

Ep300
E1A binding protein p300
MGI:1276116

Phenotype annotations related to mortality/aging

!	Indicates phenotype varies with strain background.
	Darker colors indicate more annotations

Human Phenotypes	Death in infancy
Disease(s) Associated with EP300	Death in infancy
Rubinstein-Taybi syndrome

Mouse Phenotypes		premature death	lethality throughout fetal growth and development, incomplete penetrance	perinatal lethality, complete penetrance	postnatal lethality	postnatal lethality, incomplete penetrance	embryonic lethality during organogenesis, complete penetrance	embryonic lethality during organogenesis, incomplete penetrance
Availability	Mouse Genotype	premature death		perinatal lethality, complete penetrance	postnatal lethality	postnatal lethality, incomplete penetrance
	Ep300^Plt6/Ep300^Plt6
	Ep300^tm1Dli/Ep300^tm1Dli
	Ep300^tm1Pkb/Ep300^tm1Pkb
	Ep300^tm3Pkb/Ep300^tm3Pkb
	Ep300^tm1Dli/Ep300⁺							!
	Ep300^tm1Reck/Ep300⁺
	Cd19^tm1(cre)Cgn/Cd19⁺ Ep300^tm2Reck/Ep300⁺ (conditional)	!

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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