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Symbol
Name
ID 		Chek1
checkpoint kinase 1
MGI:1202065
Phenotype annotations related to homeostasis/metabolism
Darker colors indicate more annotations
Human Phenotypes
Elevated circulating hepatic transaminase concentration
Diabetes mellitus
Disease(s) Associated with CHEK1
pancreatic cancer

Mouse Phenotypes
abnormal DNA replication
Availability Mouse Genotype
Chek1tm1Jmr/Chek1tm1Jmr
Tg(Dct-lacZ)A12Jkn/0
Tg(Tyr-cre)1Lru/Y  (conditional)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
07/14/2026
MGI 6.24 		The Jackson Laboratory