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Symbol
Name
ID

Smad3
SMAD family member 3
MGI:1201674

Phenotype annotations related to mortality/aging

!	Indicates phenotype varies with strain background.
	Darker colors indicate more annotations

Human Phenotypes	Death in early adulthood	Death in infancy	Sudden death
Disease(s) Associated with SMAD3	Death in early adulthood	Death in infancy	Sudden death
Loeys-Dietz syndrome 3
Lynch syndrome

Mouse Phenotypes		premature death	preweaning lethality, complete penetrance
Availability	Mouse Genotype	premature death	preweaning lethality, complete penetrance
	Smad3^em1(IMPC)H/Smad3^em1(IMPC)H
	Smad3^tm1Cxd/Smad3^tm1Cxd
	Smad3^tm1Par/Smad3^tm1Par	!

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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