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Symbol Name ID |
Tnfrsf9
tumor necrosis factor receptor superfamily, member 9 MGI:1101059 |
| * | Aspects of the system are reported to show a normal phenotype. |
| Darker colors indicate more annotations |
| Human Phenotypes | Decreased anti-CD3/28-induced T-cell proliferation |
Decreased circulating IgG concentration |
Complete or near-complete absence of specific antibody response to tetanus vaccine |
Decreased specific pneumococcal antibody level |
Absent circulating B cells |
Recurrent sinusitis |
Persistent EBV viremia |
Generalized lymphadenopathy |
Splenomegaly |
Recurrent lower respiratory tract infections |
| Disease(s) Associated with TNFRSF9 | ||||||||||
| immunodeficiency 109 |
| Mouse Phenotypes | immune system phenotype |
increased T cell proliferation |
increased splenocyte proliferation |
insulitis |
increased B cell number |
increased effector memory CD4-positive, alpha-beta T cell number |
increased effector memory CD8-positive, alpha-beta T cell number |
decreased CD8-positive, naive alpha-beta T cell number |
decreased CD8-positive, alpha-beta T cell number |
decreased single-positive T cell number |
abnormal immunoglobulin level |
increased IgA level |
decreased IgG2a level |
increased IgG2a level |
increased IgG2b level |
decreased IgG3 level |
abnormal T cell physiology |
abnormal cytotoxic T cell physiology |
abnormal memory T cell physiology |
decreased interferon-gamma secretion |
decreased interleukin-12 secretion |
decreased interleukin-2 secretion |
decreased interleukin-4 secretion |
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| Availability | Mouse Genotype | |||||||||||||||||||||||
| Tnfrsf9em1Ygch/Tnfrsf9em1Ygch | * | |||||||||||||||||||||||
| Tnfrsf9em2Ygch/Tnfrsf9em2Ygch | * | |||||||||||||||||||||||
| Tnfrsf9m1Btlr/Tnfrsf9m1Btlr | ||||||||||||||||||||||||
| Tnfrsf9tm1Byk/Tnfrsf9tm1Byk | ||||||||||||||||||||||||
| Tnfrsf9tm1Lpc/Tnfrsf9tm1Lpc | * | |||||||||||||||||||||||
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 01/20/2026 MGI 6.24 |
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