Symbol
Name
ID

Crebbp
CREB binding protein
MGI:1098280

Phenotype annotations related to mortality/aging

*	Aspects of the system are reported to show a normal phenotype.
!	Indicates phenotype varies with strain background.
	Darker colors indicate more annotations

Human Phenotypes	Death in infancy
Disease(s) Associated with CREBBP	Death in infancy
Rubinstein-Taybi syndrome

Mouse Phenotypes

mortality/aging

premature death

lethality throughout fetal growth and development, incomplete penetrance

perinatal lethality, incomplete penetrance

postnatal lethality

postnatal lethality, complete penetrance

postnatal lethality, incomplete penetrance

prenatal lethality

embryonic lethality during organogenesis, complete penetrance

embryonic lethality during organogenesis, incomplete penetrance

embryonic lethality, complete penetrance

prenatal lethality, incomplete penetrance

preweaning lethality, incomplete penetrance

Availability

Mouse Genotype

Crebbp^{Gt(U-San)112Imeg}/Crebbp^{Gt(U-San)112Imeg}

Crebbp^tm1.1Ltz/Crebbp^tm1.1Ltz

Crebbp^tm1Dli/Crebbp^tm1Dli

Crebbp^tm1Pkb/Crebbp^tm1Pkb

Crebbp^tm1Sis/Crebbp^tm1Sis

Crebbp^tm2Pkb/Crebbp^tm2Pkb

Crebbp^{Gt(U-San)112Imeg}/Crebbp⁺

Crebbp^tm1.1Ltz/Crebbp⁺

Crebbp^tm1Reck/Crebbp⁺

Crebbp^tm1Sis/Crebbp⁺

Crebbp^tm2Pkb/Crebbp⁺

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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