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Symbol
Name
ID
Crebbp
CREB binding protein
MGI:1098280
Phenotype annotations related to homeostasis/metabolism
Darker colors indicate more annotations
Human Phenotypes
Atypical scarring of skin
Keloids
Disease(s) Associated with CREBBP
Rubinstein-Taybi syndrome

Mouse Phenotypes
decreased susceptibility to diet-induced obesity
increased circulating glucose level
decreased circulating glucagon level
increased circulating insulin level
increased circulating leptin level
decreased circulating free fatty acids level
increased oxygen consumption
abnormal glucose homeostasis
impaired glucose tolerance
improved glucose tolerance
increased liver glycogen level
increased insulin sensitivity
insulin resistance
increased circulating adiponectin level
decreased triglyceride level
abnormal tumor necrosis factor level
Availability Mouse Genotype
Crebbptm1Few/Crebbptm1Few
CrebbpGt(U-San)112Imeg/Crebbp+
Crebbptm1Few/Crebbp+

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory