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Symbol
Name
ID

Ogg1
8-oxoguanine DNA-glycosylase 1
MGI:1097693

Phenotype annotations related to homeostasis/metabolism

Darker colors indicate more annotations

Human Phenotypes	Increased LDL cholesterol concentration	Hypercholesterolemia	Hypertriglyceridemia	Elevated circulating hepatic transaminase concentration	Glucose intolerance	Diabetes mellitus	Type II diabetes mellitus	Impaired glucose tolerance	Increased circulating free T3	Increased circulating free T4 concentration	Decreased thyroid-stimulating hormone level
Disease(s) Associated with OGG1	Increased LDL cholesterol concentration	Hypercholesterolemia	Hypertriglyceridemia	Elevated circulating hepatic transaminase concentration	Glucose intolerance	Diabetes mellitus	Type II diabetes mellitus	Impaired glucose tolerance	Increased circulating free T3	Increased circulating free T4 concentration	Decreased thyroid-stimulating hormone level
coronary artery disease
Graves' disease
pancreatic cancer

Mouse Phenotypes		increased susceptibility to neuronal excitotoxicity	abnormal DNA repair
Availability	Mouse Genotype	increased susceptibility to neuronal excitotoxicity	abnormal DNA repair
	Ogg1^tm1Tno/Ogg1^tm1Tno
	Ogg1^tm1Yun/Ogg1^tm1Yun

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/09/2024 MGI 6.23