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Symbol
Name
ID
Pten
phosphatase and tensin homolog
MGI:109583
Phenotype annotations related to vision/eye
Darker colors indicate more annotations
Human Phenotypes
Cataract
Abnormal optic nerve morphology
Angioid streaks of the fundus
Hypertelorism
Myopia
Disease(s) Associated with PTEN
Bannayan-Riley-Ruvalcaba syndrome
macrocephaly-autism syndrome

Mouse Phenotypes
abnormal optic nerve morphology
cataract
eyelids open at birth
Availability Mouse Genotype
Ptentm1Hwu/Ptentm1Hwu
Tg(Nes-cre)1Atp/0  (conditional)
Ptentm1Hwu/Ptentm1Hwu
Cnptm1(cre)Kan/Cnp+  (conditional)
Ptentm1Hwu/Ptentm1Hwu
Tg(Plp1-cre/ERT2)1Ueli/0  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory