About Help FAQ

Symbol
Name
ID

Pten
phosphatase and tensin homolog
MGI:109583

Phenotype annotations related to muscle

Darker colors indicate more annotations

Human Phenotypes	Hypotonia	Muscle weakness	Abdominal wall muscle weakness	Skeletal muscle atrophy	Myopathy
Disease(s) Associated with PTEN	Hypotonia	Muscle weakness	Abdominal wall muscle weakness	Skeletal muscle atrophy	Myopathy
Bannayan-Riley-Ruvalcaba syndrome
macrocephaly-autism syndrome

Mouse Phenotypes		increased myocardial fiber mitochondrial DNA content	increased myocardial fiber size	decreased cardiac muscle contractility	abnormal muscle fiber morphology	enhanced skeletal muscle regeneration
Availability	Mouse Genotype	increased myocardial fiber mitochondrial DNA content	increased myocardial fiber size	decreased cardiac muscle contractility	abnormal muscle fiber morphology	enhanced skeletal muscle regeneration
	Pten^tm1.1Yxy/Pten^tm1.1Yxy
	Pten^tm1Hwu/Pten^tm1Hwu (conditional)
	Pten^tm1Hwu/Pten^tm1Hwu Tg(Ckmm-cre)5Khn/? (conditional)
	Pten^tm2Mak/Pten^tm2Mak Tg(Ckmm-cre)5Khn/0 (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/16/2024 MGI 6.23