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Symbol
Name
ID
Jag1
jagged 1
MGI:1095416
Phenotype annotations related to hearing/vestibular/ear
*Aspects of the system are reported to show a normal phenotype.
Darker colors indicate more annotations
Human Phenotypes
Low-set ears
Macrotia
Protruding ear
Disease(s) Associated with JAG1
Alagille syndrome

Mouse Phenotypes
hearing/vestibular/ear phenotype
abnormal cochlea morphology
abnormal cochlear sensory epithelium morphology
abnormal cochlear hair cell morphology
abnormal cochlear hair cell number
absent cochlear hair cells
decreased cochlear outer hair cell number
absent cochlear outer hair cells
increased cochlear inner hair cell number
abnormal cochlear outer hair cell morphology
abnormal organ of Corti morphology
absent tunnel of Corti
decreased cochlea coiling
absent vestibular hair cells
abnormal semicircular canal morphology
abnormal lateral semicircular canal morphology
abnormal posterior semicircular canal morphology
abnormal semicircular canal ampulla morphology
abnormal crista ampullaris morphology
abnormal superior semicircular canal morphology
absent semicircular canals
abnormal utricular macula morphology
small utricle
abnormal vestibular saccule morphology
Availability Mouse Genotype
Jag1Mhdahtu/Jag1+ *
Jag1Slalom/Jag1+
Jag1Yo/Jag1+
Jag1tm1Jlew/Jag1tm1Jlew  (conditional)
Jag1tm1Grid/Jag1tm2Grid
Foxg1tm1(cre)Skm/Foxg1+  (conditional)
*

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory