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Symbol
Name
ID
Nfe2l2
nuclear factor, erythroid derived 2, like 2
MGI:108420
Phenotype annotations related to cellular
*Aspects of the system are reported to show a normal phenotype.
Darker colors indicate more annotations

Mouse Phenotypes
cellular phenotype
oligozoospermia
abnormal male germ cell morphology
increased mesangial cell number
abnormal cell death
increased cellular sensitivity to hydrogen peroxide
increased fibroblast apoptosis
increased male germ cell apoptosis
increased splenocyte apoptosis
increased hepatocyte apoptosis
abnormal leukocyte adhesion
asthenozoospermia
increased kidney cell proliferation
decreased hepatocyte proliferation
oxidative stress
Availability Mouse Genotype
Nfe2l2tm1Mym/Nfe2l2tm1Mym
Nfe2l2tm1Ywk/Nfe2l2tm1Ywk *
Nfe2l2tm1.1Sred/Nfe2l2tm1.1Sred
Tg(Scgb1a1-cre)1Grau/0  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory