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Symbol
Name
ID
Smo
smoothened, frizzled class receptor
MGI:108075
Phenotype annotations related to cellular
Darker colors indicate more annotations

Mouse Phenotypes
abnormal intestinal goblet cell morphology
abnormal neural crest cell apoptosis
abnormal neural crest cell migration
abnormal cardiac neural crest cell migration
decreased chondrocyte proliferation
abnormal enterocyte proliferation
Availability Mouse Genotype
Smotm2Amc/Smotm2Amc
Nkx3-2tm1(cre)Wez/Nkx3-2+  (conditional)
Smotm2Amc/Smotm2.1Amc
H2az2Tg(Wnt1-cre)11Rth/H2az2+  (conditional)
Smotm1Amc/Smotm2Amc
Isl1tm1(cre)Sev/Isl1+  (conditional)
Smotm2Amc/Smotm2.1Amc
Nkx2-5tm1(cre)Rjs/Nkx2-5+  (conditional)
Smotm1Amc/Smotm2Amc
Tg(Col2a1-cre)10Amc/0  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory