Symbol Name ID |
Srebf1
sterol regulatory element binding transcription factor 1 MGI:107606 |
* | Aspects of the system are reported to show a normal phenotype. |
Darker colors indicate more annotations |
Human Phenotypes | Increased LDL cholesterol concentration |
Hypercholesterolemia |
Hypertriglyceridemia |
Glucose intolerance |
Diabetes mellitus |
Type II diabetes mellitus |
Impaired glucose tolerance |
Insulin resistance |
Disease(s) Associated with SREBF1 | ||||||||
coronary artery disease | ||||||||
type 2 diabetes mellitus |
Mouse Phenotypes | homeostasis/metabolism phenotype |
increased circulating ketone body level |
decreased circulating cholesterol level |
decreased circulating triglyceride level |
increased liver cholesterol level |
abnormal triglyceride level |
decreased liver triglyceride level |
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Availability | Mouse Genotype | |||||||
Srebf1Gt(XC354)Byg/Srebf1Gt(XC354)Byg | ||||||||
Srebf1tm1Jdh/Srebf1tm1Jdh | ||||||||
Srebf1tm1Mbr/Srebf1tm1Mbr | * | |||||||
Srebf1tm2Jdh/Srebf1tm2Jdh |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 03/19/2024 MGI 6.23 |
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