|
Symbol Name ID |
Atm
ataxia telangiectasia mutated MGI:107202 |
| ! | Indicates phenotype varies with strain background. |
| Darker colors indicate more annotations |
| Human Phenotypes | Leukemia |
Acute lymphoblastic leukemia |
Lymphoma |
Hodgkin lymphoma |
Non-Hodgkin lymphoma |
Breast carcinoma |
Hereditary nonpolyposis colorectal carcinoma |
Colon cancer |
Neoplasm of the stomach |
Neoplasm of the liver |
Pancreatic adenocarcinoma |
Non-medullary thyroid carcinoma |
Papillary thyroid carcinoma |
Ovarian carcinoma |
Endometrial carcinoma |
Uterine leiomyosarcoma |
Renal cell carcinoma |
Transitional cell carcinoma of the bladder |
Neoplasm of the lung |
Melanoma |
| Disease(s) Associated with ATM | ||||||||||||||||||||
| ataxia telangiectasia | ||||||||||||||||||||
| breast cancer | ||||||||||||||||||||
| colorectal cancer | ||||||||||||||||||||
| endometrial cancer | ||||||||||||||||||||
| lung small cell carcinoma | ||||||||||||||||||||
| pancreatic cancer | ||||||||||||||||||||
| thyroid gland papillary carcinoma |
| Mouse Phenotypes | increased ovary tumor incidence |
increased T cell derived lymphoma incidence |
increased hepatocellular carcinoma incidence |
abnormal tumor susceptibility |
abnormal tumor incidence |
increased adenoma incidence |
increased leukemia incidence |
increased lymphoma incidence |
increased sarcoma incidence |
increased thymoma incidence |
increased tumor incidence |
|
| Availability | Mouse Genotype | |||||||||||
| Atmtm1.1Mmpl/Atmtm1.1Mmpl | ||||||||||||
| Atmtm1Awb/Atmtm1Awb | ! | ! | ! | |||||||||
| Atmtm1Bal/Atmtm1Bal | ||||||||||||
| Atmtm1Fwa/Atmtm1Fwa | ||||||||||||
| Atmtm1Led/Atmtm1Led | ||||||||||||
| Atmtm1Mfl/Atmtm1Mfl | ||||||||||||
| Atmtm1Pmc/Atmtm1Pmc | ||||||||||||
| Atmtm2.1Mfgc/Atmtm2.1Mfgc | ||||||||||||
| Atmtm1Mfl/Atm+ | ||||||||||||
| Atmtm2.1Fwa/Atmtm2.1Fwa Tg(VAV1-cre)1Graf/0 (conditional) |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/16/2024 MGI 6.23 |
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