Symbol
Name
ID

Cdc42
cell division cycle 42
MGI:106211

Phenotype annotations related to skeleton

Darker colors indicate more annotations

Mouse Phenotypes

abnormal craniofacial bone morphology

abnormal cranium morphology

abnormal frontal bone morphology

abnormal mandible morphology

maxillary shelf hypoplasia

abnormal premaxilla morphology

short premaxilla

short maxilla

abnormal nasal bone morphology

palatine bone horizontal plate hypoplasia

domed cranium

abnormal autopod joint morphology

fused phalanges

abnormal limb bone morphology

fused metacarpal bones

abnormal long bone epiphyseal plate morphology

increased width of hypertrophic chondrocyte zone

disorganized long bone epiphyseal plate

abnormal xiphoid process morphology

split sternum

abnormal cartilage development

abnormal joint morphology

abnormal intramembranous bone ossification

delayed fontanelle closure

Availability

Mouse Genotype

Cdc42^{tm1b(EUCOMM)Hmgu}/Cdc42⁺

Cdc42^tm1.1Ayam/Cdc42^tm1.1Ayam
Tg(Prrx1-cre)1Cjt/0 (conditional)

Cdc42^tm1.1Ayam/Cdc42^tm1.1Ayam
Tg(Mpz-cre)94Imeg/0 (conditional)

Cdc42^tm1.1Rac/Cdc42^tm1.1Rac
Tg(GFAP-cre)25Mes/0 (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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