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Symbol
Name
ID
Pdcd1
programmed cell death 1
MGI:104879
Phenotype annotations related to hematopoietic system
Darker colors indicate more annotations
Human Phenotypes
Internal hemorrhage
Anemia
Hemolytic anemia
Polycythemia
Leukopenia
Thrombocytopenia
Thrombocytosis
Disease(s) Associated with PDCD1
hepatocellular carcinoma
systemic lupus erythematosus

Mouse Phenotypes
increased B cell proliferation
enlarged spleen
abnormal leukopoiesis
abnormal myelopoiesis
decreased B-1 B cell number
increased B-1 B cell number
increased B cell number
increased T-helper 1 cell number
decreased CD8-positive, alpha-beta T cell number
decreased regulatory T cell number
increased regulatory T cell number
increased lymphocyte cell number
abnormal immunoglobulin level
increased IgA level
increased IgG2b level
increased IgG3 level
increased IgM level
abnormal T cell activation
Availability Mouse Genotype
Pdcd1tm1.1Liux/Pdcd1tm1.1Liux
Pdcd1tm1.1Shr/Pdcd1tm1.1Shr
Pdcd1tm1Hon/Pdcd1tm1Hon
Pdcd1tm1Llc/Pdcd1tm1Llc

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
01/17/2023
MGI 6.22
The Jackson Laboratory