|
Symbol Name ID |
Prkar1a
protein kinase, cAMP dependent regulatory, type I, alpha MGI:104878 |
| Darker colors indicate more annotations |
| Human Phenotypes | Paranasal sinus neoplasm |
Palatine myxoma |
Neoplasm of the pharynx |
Neoplasm of the breast |
Ductal carcinoma in situ |
Fibroadenoma of the breast |
Cardiac myxoma |
Esophageal neoplasm |
Neoplasm of the rectum |
Neoplasm of the stomach |
Hepatocellular carcinoma |
Neoplasm of the pancreas |
Pituitary adenoma |
Pituitary growth hormone cell adenoma |
Thyroid carcinoma |
Follicular thyroid carcinoma |
Papillary thyroid carcinoma |
Pheochromocytoma |
Leydig cell neoplasia |
Testicular neoplasm |
Sertoli cell neoplasm |
Testicular adrenal rest tumor |
Ovarian dermoid cyst |
Ovarian carcinoma |
Gonadal neoplasm |
Cutaneous myxoma |
Myxoid subcutaneous tumors |
Enchondroma |
Schwannoma |
| Disease(s) Associated with PRKAR1A | |||||||||||||||||||||||||||||
| Carney complex |
| Mouse Phenotypes | increased facial tumor incidence |
increased pituitary gland tumor incidence |
increased thyroid tumor incidence |
increased thyroid carcinoma incidence |
increased hepatocellular carcinoma incidence |
increased sarcoma incidence |
increased fibrosarcoma incidence |
increased hemangiosarcoma incidence |
increased osteosarcoma incidence |
increased Schwannoma incidence |
increased skeletal tumor incidence |
increased tumor incidence |
|
| Availability | Mouse Genotype | ||||||||||||
| Prkar1atm1.1Lsk/Prkar1a+ | |||||||||||||
| Prkar1atm1Gsm/Prkar1a+ | |||||||||||||
| Prkar1atm1.2Lsk/Prkar1atm1.2Lsk Tg(Tyr-cre)3Gfk/0 (conditional) |
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| Prkar1atm1.2Lsk/Prkar1atm1.2Lsk Tg(Ghrhr-cre)3242Lsk/0 (conditional) |
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| Prkar1atm1.2Lsk/Prkar1atm1.2Lsk Tg(TPO-cre)1Shk/0 (conditional) |
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| Prkar1atm1.2Lsk/Prkar1a+ Tg(Col1a1-cre)1Kry/0 (conditional) |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/16/2024 MGI 6.23 |
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