Symbol
Name
ID

Hand1
heart and neural crest derivatives expressed 1
MGI:103577

Phenotype annotations related to growth/size/body

Darker colors indicate more annotations

Mouse Phenotypes

enlarged heart

cardiac hypertrophy

basisphenoid bone hypoplasia

small frontal bone

frontal bone hypoplasia

small mandible

mandible hypoplasia

abnormal maxilla morphology

decreased maxillary shelf size

premaxilla hypoplasia

short premaxilla

absent nasal bone

small nasal bone

nasal bone hypoplasia

decreased palatine bone horizontal plate size

zygomatic bone hypoplasia

abnormal nasal capsule morphology

abnormal palate development

abnormal secondary palate development

abnormal palatal shelf fusion at midline

abnormal tongue position

absent nasal septum

midline facial cleft

embryonic growth retardation

decreased embryo size

decreased body length

Availability

Mouse Genotype

Hand1^tm1Eno/Hand1^tm1Eno

Hand1^{tm2(Hand1)Abfi}/Hand1^{tm2(Hand1)Abfi}

Hand1^{tm2.1(Hand1)Abfi}/Hand1^{tm2.1(Hand1)Abfi}

Hand1^tm2.1Jcc/Hand1^tm2.1Jcc

Hand1^tm2Eno/Hand1^tm3Abfi
E2f1^{Tg(Wnt1-cre)2Sor}/E2f1⁺ (conditional)

Hand1^tm2Eno/Hand1^tm4Abfi
E2f1^{Tg(Wnt1-cre)2Sor}/E2f1⁺ (conditional)

Hand1^tm3Abfi/Hand1⁺
E2f1^{Tg(Wnt1-cre)2Sor}/E2f1⁺ (conditional)

Hand1^tm4Abfi/Hand1⁺
E2f1^{Tg(Wnt1-cre)2Sor}/E2f1⁺ (conditional)

Hand1^tm3Abfi/Hand1⁺
Tg(Mpz-cre)94Imeg/0 (conditional)

Hand1^tm5Abfi/Hand1⁺
Tg(Myh6-cre)2182Mds/0 (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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