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Symbol
Name
ID

Scn8a
sodium channel, voltage-gated, type VIII, alpha
MGI:103169

Phenotype annotations related to muscle

*	Aspects of the system are reported to show a normal phenotype.
	Darker colors indicate more annotations

Human Phenotypes	Hypotonia
Disease(s) Associated with SCN8A	Hypotonia
developmental and epileptic encephalopathy 13

Mouse Phenotypes

muscle phenotype

dystonia

myoclonus

myocardial fiber degeneration

skeletal muscle necrosis

decreased skeletal muscle fiber size

dystrophic muscle

muscle degeneration

muscular atrophy

abnormal muscle physiology

impaired muscle relaxation

abnormal muscle tone

muscle weakness

progressive muscle weakness

myopathy

Availability

Mouse Genotype

Scn8a^6J/Scn8a^6J

Scn8a^7J/Scn8a^7J

Scn8a^9J/Scn8a^9J

Scn8a^dmu/Scn8a^dmu

Scn8a^m11J/Scn8a^m11J

Scn8a^med-J/Scn8a^med-J

Scn8a^med-jo/Scn8a^med-jo

*

Scn8a^med-TgA4Bs/Scn8a^med-TgA4Bs

Scn8a^med/Scn8a^med

Scn8a^dmu/Scn8a^med

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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