Symbol
Name
ID

Mybpc3
myosin binding protein C, cardiac
MGI:102844

Phenotype annotations related to muscle

Darker colors indicate more annotations

Human Phenotypes	Myopathy
Disease(s) Associated with MYBPC3	Myopathy
hypertrophic cardiomyopathy 4

Mouse Phenotypes

abnormal myocardial fiber morphology

abnormal myocardial fiber mitochondrial morphology

increased myocardial fiber size

myocardial fiber degeneration

myocardial fiber disarray

abnormal ventricle papillary muscle morphology

disorganized myocardium

heart left ventricle hypertrophy

dilated cardiomyopathy

abnormal cardiac muscle contractility

decreased cardiac muscle contractility

decreased ventricle muscle contractility

increased cardiac muscle contractility

abnormal cardiac muscle relaxation

cardiomyopathy

abnormal sarcomere morphology

abnormal M line morphology

abnormal Z line morphology

impaired muscle relaxation

Availability

Mouse Genotype

Mybpc3^tm1.1Jse/Mybpc3^tm1.1Jse

Mybpc3^tm1Jse/Mybpc3^tm1Jse

Mybpc3^tm1Lcrr/Mybpc3^tm1Lcrr

Mybpc3^tm1Rmos/Mybpc3^tm1Rmos

Mybpc3^tm2.1Lcrr/Mybpc3^tm2.1Lcrr

Mybpc3^tm1Lcrr/Mybpc3⁺

Mybpc3^tm2.1Lcrr/Mybpc3⁺

Tg(Myh6-Mybpc3*)24Rbns/0

Tg(Myh6-Mybpc3*)32Rbns/0

Mybpc3^tm2.1Rmos/Mybpc3^tm2.1Rmos
A1cf^{Tg(Myh6-cre/Esr1*)1Jmk}/A1cf⁺ (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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