Symbol
Name
ID

Nfatc1
nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 1
MGI:102469

Phenotype annotations related to cardiovascular system

Darker colors indicate more annotations

Human Phenotypes	Atrial septal defect	Ventricular septal defect	Perimembranous ventricular septal defect	Atrioventricular canal defect	Tetralogy of Fallot	Pulmonary artery stenosis	Patent ductus arteriosus	Pulmonic stenosis
Disease(s) Associated with NFATC1
ventricular septal defect

Mouse Phenotypes

abnormal cardiac outflow tract development

decreased atrioventricular cushion size

abnormal mitral valve development

abnormal tricuspid valve development

abnormal semilunar valve development

abnormal heart morphology

abnormal mitral valve cusp morphology

abnormal tricuspid valve cusp morphology

abnormal interventricular septum morphology

ventricular septal defect

cardiac hypertrophy

abnormal semilunar valve morphology

absent aortic valve cusps

absent pulmonary valve cusps

pericardial effusion

abnormal cardiovascular system physiology

abnormal blood circulation

gastrointestinal hemorrhage

semilunar valve regurgitation

Availability

Mouse Genotype

Nfatc1^tm1Glm/Nfatc1^tm1Glm

Nfatc1^tm1Mak/Nfatc1^tm1Mak

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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