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Symbol
Name
ID
Dlx5
distal-less homeobox 5
MGI:101926
Phenotype annotations related to craniofacial
Darker colors indicate more annotations
Human Phenotypes
Frontal bossing
Cleft palate
Disease(s) Associated with DLX5
split hand-foot malformation 1
split hand-foot malformation 1 with sensorineural hearing loss

Mouse Phenotypes
abnormal craniofacial bone morphology
Wormian bones
wide cranial sutures
abnormal cranium morphology
abnormal basicranium morphology
abnormal basioccipital bone morphology
abnormal basisphenoid bone morphology
abnormal styloid process morphology
short styloid process
abnormal Meckel's cartilage morphology
absent Meckel's cartilage
short Meckel's cartilage
abnormal neurocranium morphology
large anterior fontanelle
abnormal frontal bone morphology
abnormal interparietal bone morphology
small interparietal bone
abnormal occipital bone morphology
small supraoccipital bone
abnormal parietal bone morphology
small parietal bone
abnormal alisphenoid bone morphology
small presphenoid bone
abnormal pterygoid process morphology
abnormal pterygoid bone morphology
abnormal temporal bone squamous part morphology
abnormal viscerocranium morphology
abnormal hyoid bone morphology
abnormal hyoid bone greater horn morphology
abnormal hyoid bone lesser horn morphology
abnormal jaw morphology
abnormal incisor morphology
short lower incisors
short upper incisors
abnormal molar morphology
abnormal molar crown morphology
abnormal tooth mineralization
abnormal mandible morphology
abnormal mandibular angle morphology
abnormal mandibular condyloid process morphology
abnormal mandibular coronoid process morphology
absent mandibular coronoid process
short mandible
abnormal maxilla morphology
decreased maxillary shelf size
abnormal premaxilla morphology
short premaxilla
small maxilla
short maxilla
lower jaw to upper jaw transformation
micrognathia
abnormal lacrimal bone morphology
small lacrimal bone
abnormal nasal bone morphology
small nasal bone
short nasal bone
absent palatine bone horizontal plate
turbinate hypoplasia
abnormal vomer bone morphology
small vomer bone
abnormal zygomatic bone morphology
ectopic cranial bone
abnormal middle ear ossicle morphology
abnormal malleus morphology
abnormal gonial bone morphology
small malleus processus brevis
absent stapes
abnormal craniofacial development
abnormal frontonasal prominence morphology
frontonasal prominence hypoplasia
abnormal lateral nasal prominence morphology
abnormal mandibular prominence morphology
abnormal nasal capsule morphology
abnormal nasal pit morphology
abnormal pharyngeal arch morphology
abnormal first pharyngeal arch morphology
fused pharyngeal arches
abnormal pterygoid muscle morphology
abnormal mouth morphology
abnormal palate morphology
cleft primary palate
cleft secondary palate
abnormal tongue muscle morphology
abnormal intrinsic tongue muscle morphology
abnormal nasal mucosa morphology
absent vomeronasal organ
small vomeronasal organ
deviated nasal septum
short nasal septum
abnormal olfactory epithelium morphology
absent olfactory epithelium
abnormal snout morphology
short snout
abnormal outer ear morphology
abnormal external auditory canal morphology
abnormal outer ear cartilage morphology
Availability Mouse Genotype
Dlx5/Dlx6tm1Levi/Dlx5/Dlx6tm1Levi
Dlx5tm1Jlr/Dlx5tm1Jlr
Dlx5tm1Levi/Dlx5tm1Levi

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory