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Phenotypes associated with Nlgn3tm1Sud/Y Tg(Drd1-cre)EY262Gsat/0
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cn1
Nlgn3tm1Sud/Y
Tg(Drd1-cre)EY262Gsat/0
involves: 129S1/Sv * 129X1/SvJ * FVB/N MGI:5660866

Comparison Matrix Gene Expression + Phenotype


Genotype
MGI:5660866
cn1
Allelic
Composition
Nlgn3tm1Sud/Y
Tg(Drd1-cre)EY262Gsat/0
Genetic
Background
involves: 129S1/Sv * 129X1/SvJ * FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Nlgn3tm1Sud mutation (1 available); any Nlgn3 mutation (35 available)
Tg(Drd1-cre)EY262Gsat mutation (2 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
behavior/neurological
• mice exhibit increased learning rate but similar initial coordination on the accelerating rotarod
• mice perform similarly to wild-type littermates on the first trial of an accelerating rotarod, however in the last several trials, mice exhibit enhanced performance, with increased time on the rotarod before falling off compared to wild-type mice, indicating enhanced formation of repetitive motor routine



Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory