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Gene Expression Data
Assay Details
Assay
Reference: J:335681 Schlienger S, et al., Genetics of mirror movements identifies a multifunctional complex required for Netrin-1 guidance and lateralization of motor control. Sci Adv. 2023 May 12;9(19):eadd5501
Assay type: Immunohistochemistry
MGI Accession ID: MGI:8210426
Gene symbol: Arhgef7
Gene name: Rho guanine nucleotide exchange factor
Results
Specimen 2C E10.5: embryonic day 10.5 (more )
Note: Section from the level of the forelimb. Double labeled: green - Arhgef7; red - Robo3 (assay MGI:8210427).
Structure Cell Type Level Pattern Image Note
TS17: future spinal cord Present Widespread 2C E10.5 Arhgef7/Robo3 zoom , 2C E10.5 Arhgef7/Robo3 , 2C E10.5 Arhgef7 Arhgef7 is widely expressed throughout the spinal cord.
TS17: future spinal cord commissural neuron Present 2C E10.5 Arhgef7 , 2C E10.5 Arhgef7/Robo3 zoom , 2C E10.5 Arhgef7/Robo3 Arhgef7 colocalizes with Robo3, a marker of commissural neurons. Arhgef7 appears to be present in pre- and postcrossing commissural axons.
Specimen 2C E11.5: embryonic day 11.5 (more )
Note: Section from the level of the forelimb. Double labeled: green - Arhgef7; red - Robo3 (assay MGI:8210427).
Structure Cell Type Level Pattern Image Note
TS19: future spinal cord Present Widespread 2C E11.5 Arhgef7/Robo3 zoom , 2C E11.5 Arhgef7 , 2C E11.5 Arhgef7/Robo3 Arhgef7 is widely expressed throughout the spinal cord.
TS19: future spinal cord commissural neuron Present 2C E11.5 Arhgef7 , 2C E11.5 Arhgef7/Robo3 zoom , 2C E11.5 Arhgef7/Robo3 Arhgef7 colocalizes with Robo3, a marker of commissural neurons. Arhgef7 appears to be present in pre- and postcrossing commissural axons.
Specimen S1C Control: embryonic day 7.5 (more )
Structure Level Pattern Image Note
TS11: embryo Present S1C Control Arhgef7-DAPI , S1C Control Arhgef7 zoom , S1C Control Arhgef7
Specimen S1C Arhgef7-/-: embryonic day 7.5; Arhgef7tm1b(EUCOMM)Wtsi/Arhgef7tm1b(EUCOMM)Wtsi (more )
Structure Level Pattern Image Note
TS11: embryo Absent S1C Arhgef7-/- Arhgef7 , S1C Arhgef7-/- Arhgef7-DAPI , S1C Arhgef7-/- Arhgef7 zoom
Specimen S1D: embryonic day 11.5 (more )
Note: Section from the level of the forelimb.
Structure Level Pattern Image Note
TS19: future spinal cord Present Widespread S1D Arhgef7 , S1D Arhgef7 zoom
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory