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Gene Expression Data
Assay Details
Assay
Reference: J:360776 Di Michele M, et al., E4F1 coordinates pyruvate metabolism and the activity of the elongator complex to ensure translation fidelity during brain development. Nat Commun. 2025 Jan 2;16(1):67
Assay type: Western blot
MGI Accession ID: MGI:8188159
Gene symbol: Pdha1
Gene name: pyruvate dehydrogenase E1 alpha 1
Antibody: anti-PDHA1
Results
Image: 4B PDHA1 ©

 Sample Information Bands Other Sample Information
Lane AgeStructure Size Not Specified Genetic BackgroundMutant Allele(s)Sex Note
CTL #1 E14.5 TS22: brain Present involves: 129/Sv * C57BL/6J Not Specified
KO #1 E14.5 TS22: brain Present involves: 129/Sv * C57BL/6 * C57BL/6J * SJL E4f1tm1.1Llca/E4f1tm1.1Llca, Gt(ROSA)26Sortm1(cre/ERT2)Tyj/Gt(ROSA)26Sor+, Tg(Nes-cre)1Kln/0Not Specified Conditional mutant.
CTL #2 E14.5 TS22: brain Present involves: 129/Sv * C57BL/6J Not Specified
KO #2 E14.5 TS22: brain Present (a) involves: 129/Sv * C57BL/6 * C57BL/6J * SJL E4f1tm1.1Llca/E4f1tm1.1Llca, Gt(ROSA)26Sortm1(cre/ERT2)Tyj/Gt(ROSA)26Sor+, Tg(Nes-cre)1Kln/0Not Specified Conditional mutant.
Notes:
(a) Expression levels unaffected compared to control.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory