Key:
hm homozygous ht heterozygous tg involves transgenes phenotype observed
cn conditional genotype  cx complex: > 1 genome feature ot other: hemizygous, indeterminate,... N normal phenotype
Genotype/
Background:
Phenotypes:
Affected Systems
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IMPC - TCP
IMPC - TCP
IMPC - TCP
adipose tissue
increased total body fat amount
embryo
abnormal embryo size
abnormal neural tube closure
growth/size/body
abnormal embryo size
decreased lean body mass
mortality/aging
preweaning lethality, complete penetrance
nervous system
abnormal neural tube closure
reproductive system
abnormal uterus morphology