Key:

hm	homozygous	ht	heterozygous	tg	involves transgenes	√	phenotype observed
cn	conditional genotype	cx	complex: > 1 genome feature	ot	other: hemizygous, indeterminate,...	N	normal phenotype

Genotype/
Background:

Phenotypes:

Affected Systems	hm1
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cardiovascular system	√
distended pericardium	√
digestive/alimentary system	√
abnormal hindgut morphology	√
embryo	√
abnormal embryo development	√
abnormal developmental patterning	√
failure of initiation of embryo turning	√
caudal body truncation	√
abnormal embryonic tissue morphology	√
abnormal neural tube closure	√
abnormal caudal neuropore morphology	√
abnormal primitive streak morphology	√
incomplete somite formation	√
abnormal extraembryonic tissue morphology	√
abnormal allantois morphology	√
enlarged allantois	√
abnormal chorion morphology	√
failure of chorioallantoic fusion	√
growth/size/body	√
abnormal ventral body wall morphology	√
mortality/aging	√
embryonic lethality during organogenesis, complete penetrance	√
nervous system	√
abnormal neural tube closure	√
abnormal caudal neuropore morphology	√
abnormal brain development	√
abnormal cranial nerve morphology	√
abnormal oculomotor nerve morphology	√
abnormal trochlear nerve morphology	√
skeleton	√
abnormal spine curvature	√