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Phenotypes Associated with This Genotype
Genotype
MGI:6515776
Allelic
Composition
Slc25a17Gt(XB686)Byg/Slc25a17Gt(XB686)Byg
Genetic
Background
involves: 129P2/OlaHsd * C57BL/6 * Swiss Webster
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Slc25a17Gt(XB686)Byg mutation (1 available); any Slc25a17 mutation (71 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
mortality/aging
N
• Background Sensitivity: unlike on a mixed background with only 129P2/OlaHsd and C57BL/6, mice in a mixed background including Swiss Webster exhibit normal Mendelian ratio at birth

liver/biliary system
• enlarged in mice fed a phytol-rich diet
• apoptotic bodies in mice fed a phytol-rich diet
• in mice fed a phytol-rich diet
• acute in mice fed a phytol-rich diet
• microvesicular steatosis (including increased cholesterylesters, pristanic acid, phytanic in female and males; triacylglyerol in male mice) with reduced arachidonic acid and DHA in mice fed a phytol-rich diet
• however, levels of very long chain fatty acids are normal

cardiovascular system
• enlarged in mice fed a phytol-rich diet

growth/size/body
• in mice fed a phytol-rich diet

hematopoietic system
• enlarged in mice fed a phytol-rich diet

immune system
• enlarged in mice fed a phytol-rich diet
• acute in mice fed a phytol-rich diet

cellular
• apoptotic bodies in mice fed a phytol-rich diet


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory