Phenotypes Associated with This Genotype

Genotype
MGI:4822059

• Allelic Composition: Ccn2^tm1Mga/Ccn2⁺
• Genetic Background: involves: 129S6/SvEvTac * C57BL/6NTac

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

skeleton

decreased bone mineral density ( J:163027 )

• at 1 month of age the bone volume to tissue volume ratio is reduced by 30-45%

• however, by 4 and 6 months of age no difference in the bone volume to tissue volume ratio is detected

abnormal trabecular bone morphology ( J:163027 )

• at 1 month of age the number of trabeculae is reduced but trabecular thickness is not significantly reduced