Phenotypes for Cnga2 MGI:3717661 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Cnga2^tm1Ngai/Cnga2^tm1Ngai
Genetic Background	involves: 129S1/Sv * FVB/N

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Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cnga2^tm1Ngai mutation (1 available); any Cnga2 mutation (15 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

taste/olfaction

abnormal olfactory system physiology ( J:96894 )

• lilial, octaldehyde, N-pentyl acetate, geraniol, citral, kovanol, valeric acid, ethyl priopionate, menthone, ethyl acetate and 1um forskolin fail to elicit an odor-evoked field potential at low concentration whereas a small response is elicited at high concentration (1-5mM)

• 2,5-dimethyl pyrazine (DMP) and 2-heptanone activate a small number of glomeruli within the olfactory bulb

• 1/40x 1% ethyl acetate activated 3 glomeruli distinct from those activated by DMP and 2-heptanone

abnormal olfaction ( J:96894 )

• mice cannot detect lilial, octaldehyde, N-pentyl acetate and geraniol

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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