Phenotypes Associated with This Genotype

Genotype
MGI:3607451

• Allelic Composition: Nectin3^tm1Ytk/Nectin3^tm1Ytk
• Genetic Background: either: (involves: 129X1/SvJ * C57BL * DBA) or (involves: 129X1/SvJ * BALB/cA * C57BL * DBA)

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

reproductive system

male infertility ( J:101707 )

♂

vision/eye

abnormal anterior eye segment morphology ( J:101707 )

abnormal ciliary epithelium morphology ( J:101707 )

• ciliary epithelia adhere to the lens

• separation of the apex-apex contact between the pigment and non-pigment cell layers of the ciliary epithelia at E16.5, however no impairment of the apicolateral junctions between the pigment epithelia or the apicolateral junctions between the non-pigment epithelia

absent ciliary process ( J:101707 )

• ciliary processes are absent

abnormal lens morphology ( J:101707 )

• lenses are somewhat deformed

microphthalmia ( J:101707 )

abnormal retina layer morphology ( J:101707 )

• retinal layers are undulating

abnormal vitreous body morphology ( J:101707 )

• vitreous body is absent