Phenotypes Associated with This Genotype

Genotype
MGI:3034063

• Allelic Composition: Nfkbie^tm1Syme/Nfkbie^tm1Syme
• Genetic Background: either: (involves: 129P2/OlaHsd * C57BL/6 * DBA/2) or (involves: 129P2/OlaHsd * C57BL/6)

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

hematopoietic system

abnormal double-negative T cell morphology ( J:88538 )

• 50% reduction of CD44-/CD25+ double negative cells

• only lymphocyte abnormality

increased IgG1 level ( J:88538 )

• IgG1 levels increased 3X

increased IgM level ( J:88538 )

• 2 fold increase

immune system

abnormal double-negative T cell morphology ( J:88538 )

• 50% reduction of CD44-/CD25+ double negative cells

• only lymphocyte abnormality

increased IgG1 level ( J:88538 )

• IgG1 levels increased 3X

increased IgM level ( J:88538 )

• 2 fold increase

skeleton

skeleton phenotype ( J:88538 )

N • skeleton was normal