Rapgef1^tm1.1Awp
Targeted Allele Detail

Summary

• Symbol: Rapgef1^tm1.1Awp
• Name: Rap guanine nucleotide exchange factor (GEF) 1; targeted mutation 1.1, Andreas W Puschel
• MGI ID: MGI:8163431
• Synonyms: Rapgef1^flox
• Gene: Rapgef1 Location: Chr2:29509732-29630376 bp, + strand Genetic Position: Chr2, 20.32 cM, cytoband B
• Alliance: Rapgef1^tm1.1Awp page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:248896
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6N

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: Exons 1721 were flanked with LoxP sites and an frt-flanked neomycin selection cassette. The selection cassette was removed via FLP-mediated recombination in the germline. (J:248896)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Rapgef1 Mutation: 192 strains or lines available

References

• Original: J:248896 Shah B, et al., C3G/Rapgef1 Is Required in Multipolar Neurons for the Transition to a Bipolar Morphology during Cortical Development. PLoS One. 2016;11(4):e0154174
• All: 3 reference(s)