Cd44tm1.1Mka
Targeted Allele Detail
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Symbol: |
Cd44tm1.1Mka |
Name: |
CD44 antigen; targeted mutation 1.1, Michael Karin |
MGI ID: |
MGI:6468303 |
Synonyms: |
Cd44F |
Gene: |
Cd44 Location: Chr2:102641486-102732010 bp, - strand Genetic Position: Chr2, 54.13 cM
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Alliance: |
Cd44tm1.1Mka page
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Germline Transmission: |
Earliest citation of germline transmission:
J:262540
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Parent Cell Line: |
Not Specified (ES Cell)
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Strain of Origin: |
129S/SvEv
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Allele Type: |
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Targeted (Conditional ready) |
Mutation: |
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Insertion
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Mutation details: Exon 3 was flanked with loxP sites. An frt-flanked neomycin selection cassette was removed in ES cells prior to the creation of chimeric mice.
(J:262540)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Cd44 Mutation: |
67 strains or lines available
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Original: |
J:262540 Dhar D, et al., Liver Cancer Initiation Requires p53 Inhibition by CD44-Enhanced Growth Factor Signaling. Cancer Cell. 2018 Jun 11;33(6):1061-1077.e6 |
All: |
3 reference(s) |
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