Cd5^tm1.1Hhw
Targeted Allele Detail

Summary

• Symbol: Cd5^tm1.1Hhw
• Name: CD5 antigen; targeted mutation 1.1, Henry H Wortis
• MGI ID: MGI:4880745
• Synonyms: Enh^-
• Gene: Cd5 Location: Chr19:10695471-10716390 bp, - strand Genetic Position: Chr19, 7.16 cM
• Alliance: Cd5^tm1.1Hhw page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:167469
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: BALB/c

Mutation description

• Allele Type: Targeted (Modified regulatory region)
• Mutations: Insertion, Intragenic deletion
• Mutation details: An upstream enhancer was replaced with a floxed neo cassette. Cre-mediated recombination removed the neo cassette. (J:167469)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Cd5 Mutation: 34 strains or lines available

References

• Original: J:167469 Berland R, et al., A conserved enhancer element differentially regulates developmental expression of CD5 in B and T cells. J Immunol. 2010 Dec 15;185(12):7537-43
• All: 1 reference(s)