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Targeted Allele Detail
Symbol: Card6tm1Aldu
Name: caspase recruitment domain family, member 6; targeted mutation 1, Almut Dufner
MGI ID: MGI:3776907
Gene: Card6  Location: Chr15:5125463-5138021 bp, - strand  Genetic Position: Chr15, 1.99 cM
Alliance: Card6tm1Aldu page
Germline Transmission:  Earliest citation of germline transmission: J:132634
Parent Cell Line:  E14K (ES Cell)
Strain of Origin:  129P2/OlaHsd
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
Mutation detailsAn frt-flanked neo cassette with a 3' loxP site was inserted upstream of the fourth coding exon and an additional loxP site was inserted downstream of the coding region. (J:132634)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Card6 Mutation:  54 strains or lines available
Original:  J:132634 Dufner A, et al., CARD6 is interferon inducible but not involved in nucleotide-binding oligomerization domain protein signaling leading to NF-kappaB activation. Mol Cell Biol. 2008 Mar;28(5):1541-52
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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MGI 6.13
The Jackson Laboratory