Compare GO annotations for TLR4 and its OrthoDisease orthologs

Compare GO annotations for TLR4 and its orthologs

A table of the annotations represented in this image is provided below.

Annotations are indicated by colored nodes: mouse, human, rat, worm, fly, dicty, chicken, zfin, rice, tair, yeast, pombe, pfalc, and multiple.
Green arrows indicate "is_a"; Purple arrows indicate "part_of"
GO annotations: Mouse from MGI; Human from GO Annotations @ EBI (GOA); Rat from RGD; Chicken from GOA; Fly from FlyBase; Pfalc from PlasmoDB; Worm from WormBase; Dicty from dictyBase; Yeast from SGD; Zfin from ZFIN; Tair from TAIR/TIGR; Rice from Gramene; Pombe from Sanger GeneDB.
Does not include evidence codes: IEA, ISS, RCA, NR, ND, NAS, IC, IGC, TAS.
Graph is also available as SVG (requires viewer plug-in from Adobe)
All nodes are linked to the MGI GO browser.
Graph generated Fri Dec 7 09:49:59 2007.

Category	ID	Term	DB Object	Evidence	Organism	Reference
Molecular Function	GO:0043548	phosphoinositide 3-kinase binding	RGD:3870	IPI	Rat	RGD:1302746\|PMID:14962484
Molecular Function	GO:0005515	protein binding	MGI:96824	IPI	Mouse	PMID:17803912
Molecular Function	GO:0005515	protein binding	O00206	IPI	Human	PMID:11544529
Molecular Function	GO:0005515	protein binding	RGD:3870	IPI	Rat	RGD:1302746\|PMID:14962484
Molecular Function	GO:0004872	receptor activity	RGD:3870	IDA	Rat	RGD:634467\|PMID:12616494
Cellular Component	GO:0009986	cell surface	RGD:3870	IDA	Rat	RGD:1598585\|PMID:16847070
Cellular Component	GO:0005737	cytoplasm	RGD:3870	IDA	Rat	RGD:1598585\|PMID:16847070
Cellular Component	GO:0045121	lipid raft	RGD:3870	IDA	Rat	RGD:1598585\|PMID:16847070
Biological Process	GO:0051092	activation of NF-kappaB transcription factor	RGD:3870	IMP	Rat	RGD:1598593\|PMID:16651628
Biological Process	GO:0006954	inflammatory response	RGD:3870	IEP	Rat	RGD:1624166\|PMID:15204789
Biological Process	GO:0042116	macrophage activation	O00206	IMP	Human	PMID:10835634
Biological Process	GO:0043065	positive regulation of apoptosis	RGD:3870	IMP	Rat	RGD:1598594\|PMID:16272348
Biological Process	GO:0043388	positive regulation of DNA binding	RGD:3870	IMP	Rat	RGD:1598594\|PMID:16272348
Biological Process	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB cascade	MGI:96824	IDA	Mouse	MGI:MGI:3607973\|PMID:16260493
Biological Process	GO:0050729	positive regulation of inflammatory response	RGD:3870	IMP	Rat	RGD:1598593\|PMID:16651628
Biological Process	GO:0046330	positive regulation of JNK cascade	MGI:96824	IDA	Mouse	MGI:MGI:3607973\|PMID:16260493
Biological Process	GO:0046330	positive regulation of JNK cascade	MGI:96824	IGI	Mouse	MGI:MGI:3607973\|PMID:16260493
Biological Process	GO:0050731	positive regulation of peptidyl-tyrosine phosphorylation	RGD:3870	IDA	Rat	RGD:634467\|PMID:12616494
Biological Process	GO:0051091	positive regulation of transcription factor activity	RGD:3870	IMP	Rat	RGD:1598594\|PMID:16272348
Biological Process	GO:0009617	response to bacterium	MGI:96824	IMP	Mouse	MGI:MGI:3608578\|PMID:11294571
Biological Process	GO:0045471	response to ethanol	RGD:3870	IMP	Rat	RGD:1598594\|PMID:16272348
Biological Process	GO:0032496	response to lipopolysaccharide	RGD:3870	IEP	Rat	RGD:1620770\|PMID:17167854
Biological Process	GO:0006979	response to oxidative stress	RGD:3870	IMP	Rat	RGD:1598585\|PMID:16847070