Compare GO annotations for INS and its OrthoDisease orthologs

Compare GO annotations for INS and its orthologs

A table of the annotations represented in this image is provided below.

Annotations are indicated by colored nodes: mouse, human, rat, worm, fly, dicty, chicken, zfin, rice, tair, yeast, pombe, pfalc, and multiple.
Green arrows indicate "is_a"; Purple arrows indicate "part_of"
GO annotations: Mouse from MGI; Human from GO Annotations @ EBI (GOA); Rat from RGD; Chicken from GOA; Fly from FlyBase; Pfalc from PlasmoDB; Worm from WormBase; Dicty from dictyBase; Yeast from SGD; Zfin from ZFIN; Tair from TAIR/TIGR; Rice from Gramene; Pombe from Sanger GeneDB.
Does not include evidence codes: IEA, ISS, RCA, NR, ND, NAS, IC, IGC, TAS.
Graph is also available as SVG (requires viewer plug-in from Adobe)
All nodes are linked to the MGI GO browser.
Graph generated Fri Dec 7 09:49:59 2007.

Category	ID	Term	DB Object	Evidence	Organism	Reference
Molecular Function	GO:0005158	insulin receptor binding	P01308	IDA	Human	PMID:7556975
Molecular Function	GO:0005520	insulin-like growth factor binding	P01308	IPI	Human	PMID:9388210
Molecular Function	GO:0005515	protein binding	P01308	IPI	Human	PMID:9773776
Cellular Component	GO:0005634	nucleus	MGI:96573	IDA	Mouse	MGI:MGI:2447254\|PMID:12488434
Cellular Component	GO:0030141	secretory granule	MGI:96573	IDA	Mouse	MGI:MGI:3589494\|PMID:15788565
Cellular Component	GO:0005732	small nucleolar ribonucleoprotein complex	MGI:96573	IDA	Mouse	MGI:MGI:2447254\|PMID:12488434
Biological Process	GO:0000187	activation of MAPK activity	MGI:96573	IDA	Mouse	MGI:MGI:2387283\|PMID:12059784
Biological Process	GO:0046631	alpha-beta T cell activation	P01308	IDA	Human	PMID:10604997
Biological Process	GO:0006983	ER overload response	MGI:96573	IMP	Mouse	MGI:MGI:2158984\|PMID:11854325
Biological Process	GO:0006006	glucose metabolic process	MGI:96573	IMP	Mouse	MGI:MGI:2158984\|PMID:11854325
Biological Process	GO:0015758	glucose transport	P01308	IDA	Human	PMID:15792832
Biological Process	GO:0015758	glucose transport	P01308	IDA	Human	PMID:14615391
Biological Process	GO:0008286	insulin receptor signaling pathway	MGI:96573	IDA	Mouse	MGI:MGI:2664440\|PMID:12805218
Biological Process	GO:0016042	lipid catabolic process	MGI:96573	IDA	Mouse	MGI:MGI:2664440\|PMID:12805218
Biological Process	GO:0042177	negative regulation of protein catabolic process	P01308	IDA	Human	PMID:15185208
Biological Process	GO:0000122	negative regulation of transcription from RNA polymerase II promoter	MGI:96573	IDA	Mouse	MGI:MGI:1276655\|PMID:9689059
Biological Process	GO:0050715	positive regulation of cytokine secretion	P01308	IDA	Human	PMID:15473891
Biological Process	GO:0042981	regulation of apoptosis	MGI:96573	IMP	Mouse	MGI:MGI:2158984\|PMID:11854325
Biological Process	GO:0042325	regulation of phosphorylation	MGI:96573	IDA	Mouse	MGI:MGI:2387283\|PMID:12059784
Biological Process	GO:0050708	regulation of protein secretion	P01308	IDA	Human	PMID:15591776