Compare GO annotations for ESR1 and its OrthoDisease orthologs

Compare GO annotations for ESR1 and its orthologs

A table of the annotations represented in this image is provided below.

Annotations are indicated by colored nodes: mouse, human, rat, worm, fly, dicty, chicken, zfin, rice, tair, yeast, pombe, pfalc, and multiple.
Green arrows indicate "is_a"; Purple arrows indicate "part_of"
GO annotations: Mouse from MGI; Human from GO Annotations @ EBI (GOA); Rat from RGD; Chicken from GOA; Fly from FlyBase; Pfalc from PlasmoDB; Worm from WormBase; Dicty from dictyBase; Yeast from SGD; Zfin from ZFIN; Tair from TAIR/TIGR; Rice from Gramene; Pombe from Sanger GeneDB.
Does not include evidence codes: IEA, ISS, RCA, NR, ND, NAS, IC, IGC, TAS.
Graph is also available as SVG (requires viewer plug-in from Adobe)
All nodes are linked to the MGI GO browser.
Graph generated Fri Dec 7 09:49:59 2007.

Category	ID	Term	DB Object	Evidence	Organism	Reference
Molecular Function	GO:0003677	DNA binding	RGD:2581	IMP	Rat	RGD:1358611\|PMID:12372009
Molecular Function	GO:0030284	estrogen receptor activity	RGD:2581	IDA	Rat	RGD:1580331\|PMID:15105439
Molecular Function	GO:0042562	hormone binding	RGD:2581	IMP	Rat	RGD:1580331\|PMID:15105439
Molecular Function	GO:0004879	ligand-dependent nuclear receptor activity	MGI:1352467	IDA	Mouse	MGI:MGI:3512848\|PMID:15322135
Molecular Function	GO:0005515	protein binding	MGI:1352467	IPI	Mouse	MGI:MGI:3687892\|PMID:12878603
Molecular Function	GO:0005515	protein binding	MGI:1352467	IPI	Mouse	MGI:MGI:84614\|PMID:8978696
Molecular Function	GO:0047485	protein N-terminus binding	P03372	IPI	Human	PMID:12917342
Molecular Function	GO:0030528	transcription regulator activity	MGI:1352467	IDA	Mouse	MGI:MGI:3512848\|PMID:15322135
Cellular Component	GO:0005737	cytoplasm	MGI:1352467	IDA	Mouse	MGI:MGI:3617027\|PMID:12845704
Cellular Component	GO:0005737	cytoplasm	RGD:2581	IDA	Rat	RGD:1582179\|PMID:16122717
Cellular Component	GO:0005737	cytoplasm	RGD:2581	IDA	Rat	RGD:1601101\|PMID:16869728
Cellular Component	GO:0043005	neuron projection	RGD:2581	IDA	Rat	RGD:1582179\|PMID:16122717
Cellular Component	GO:0005634	nucleus	MGI:1352467	IDA	Mouse	MGI:MGI:3617027\|PMID:12845704
Cellular Component	GO:0005634	nucleus	MGI:1352467	IDA	Mouse	MGI:MGI:2178020\|PMID:11897499
Cellular Component	GO:0005634	nucleus	MGI:1352467	IDA	Mouse	MGI:MGI:86051\|PMID:8999954
Cellular Component	GO:0005634	nucleus	RGD:2581	IMP	Rat	RGD:1358611\|PMID:12372009
Cellular Component	GO:0005634	nucleus	RGD:2581	IDA	Rat	RGD:1582179\|PMID:16122717
Cellular Component	GO:0005634	nucleus	RGD:2581	IDA	Rat	RGD:1601101\|PMID:16869728
Cellular Component	GO:0043204	perikaryon	RGD:2581	IDA	Rat	RGD:1582179\|PMID:16122717
Cellular Component	GO:0005886	plasma membrane	RGD:2581	IDA	Rat	RGD:1601102\|PMID:16876190
Cellular Component	GO:0030315	T-tubule	RGD:2581	IDA	Rat	RGD:1601102\|PMID:16876190
Cellular Component	GO:0043195	terminal button	RGD:2581	IDA	Rat	RGD:1601103\|PMID:17314305
Biological Process	GO:0043526	neuroprotection	RGD:2581	IDA	Rat	RGD:1582270\|PMID:15126114
Biological Process	GO:0045885	positive regulation of survival gene product activity	RGD:2581	IDA	Rat	RGD:1582270\|PMID:15126114
Biological Process	GO:0043627	response to estrogen stimulus	RGD:2581	IPI	Rat	RGD:1625219\|PMID:16971528