Compare GO annotations for EGFR and its OrthoDisease orthologs

Compare GO annotations for EGFR and its orthologs

A table of the annotations represented in this image is provided below.

Annotations are indicated by colored nodes: mouse, human, rat, worm, fly, dicty, chicken, zfin, rice, tair, yeast, pombe, pfalc, and multiple.
Green arrows indicate "is_a"; Purple arrows indicate "part_of"
GO annotations: Mouse from MGI; Human from GO Annotations @ EBI (GOA); Rat from RGD; Chicken from GOA; Fly from FlyBase; Pfalc from PlasmoDB; Worm from WormBase; Dicty from dictyBase; Yeast from SGD; Zfin from ZFIN; Tair from TAIR/TIGR; Rice from Gramene; Pombe from Sanger GeneDB.
Does not include evidence codes: IEA, ISS, RCA, NR, ND, NAS, IC, IGC, TAS.
Graph is also available as SVG (requires viewer plug-in from Adobe)
All nodes are linked to the MGI GO browser.
Graph generated Fri Dec 7 09:49:59 2007.

Category	ID	Term	DB Object	Evidence	Organism	Reference
Molecular Function	GO:0051015	actin filament binding	P00533	IDA	Human	PMID:14702346
Molecular Function	GO:0005006	epidermal growth factor receptor activity	MGI:95294	IDA	Mouse	MGI:MGI:3032880\|PMID:14712229
Molecular Function	GO:0005006	epidermal growth factor receptor activity	P00533	IDA	Human	PMID:12435727
Molecular Function	GO:0005006	epidermal growth factor receptor activity	RGD:2543	IDA	Rat	RGD:70386\|PMID:11796513
Molecular Function	GO:0042802	identical protein binding	P00533	IPI	Human	PMID:16777603
Molecular Function	GO:0016301	kinase activity	MGI:95294	IDA	Mouse	MGI:MGI:2664443\|PMID:12808090
Molecular Function	GO:0030235	nitric-oxide synthase regulator activity	P00533	IDA	Human	PMID:12828935
Molecular Function	GO:0005515	protein binding	MGI:95294	IPI	Mouse	MGI:MGI:3531070\|PMID:15695332
Molecular Function	GO:0005515	protein binding	MGI:95294	IPI	Mouse	MGI:MGI:3587490\|PMID:15728722
Molecular Function	GO:0005515	protein binding	MGI:95294	IPI	Mouse	MGI:MGI:3722980\|PMID:17726113
Molecular Function	GO:0005515	protein binding	MGI:95294	IPI	Mouse	MGI:MGI:2429328\|PMID:11274221
Molecular Function	GO:0005515	protein binding	MGI:95294	IPI	Mouse	MGI:MGI:2675970\|PMID:12919676
Molecular Function	GO:0046982	protein heterodimerization activity	P00533	IDA	Human	PMID:10572067
Molecular Function	GO:0004871	signal transducer activity	MGI:95294	IDA	Mouse	MGI:MGI:2182234\|PMID:11940581
Molecular Function	GO:0004888	transmembrane receptor activity	P00533	IDA	Human	PMID:7736574
Cellular Component	GO:0016323	basolateral plasma membrane	MGI:95294	IDA	Mouse	MGI:MGI:70770\|PMID:7723235
Cellular Component	GO:0005737	cytoplasm	P00533	IDA	Human	PMID:12435727
Cellular Component	GO:0030139	endocytic vesicle	MGI:95294	IDA	Mouse	MGI:MGI:1349243\|PMID:10534613
Cellular Component	GO:0030139	endocytic vesicle	RGD:2543	IDA	Rat	RGD:1581916\|PMID:11071913
Cellular Component	GO:0005768	endosome	P00533	IDA	Human	PMID:14702346
Cellular Component	GO:0005622	intracellular	MGI:95294	IDA	Mouse	MGI:MGI:1349243\|PMID:10534613
Cellular Component	GO:0005634	nucleus	P00533	IDA	Human	PMID:12828935
Cellular Component	GO:0005886	plasma membrane	MGI:95294	IDA	Mouse	MGI:MGI:75839\|PMID:7641815
Cellular Component	GO:0005886	plasma membrane	P00533	IDA	Human	PMID:15465819
Cellular Component	GO:0005886	plasma membrane	RGD:2543	IDA	Rat	RGD:1581916\|PMID:11071913
Biological Process	GO:0000186	activation of MAPKK activity	RGD:2543	IMP	Rat	RGD:1581912\|PMID:14551192
Biological Process	GO:0048143	astrocyte activation	RGD:2543	IMP	Rat	RGD:1581900\|PMID:16837601
Biological Process	GO:0007166	cell surface receptor linked signal transduction	P00533	IDA	Human	PMID:7736574
Biological Process	GO:0016337	cell-cell adhesion	P00533	IMP	Human	PMID:12435727
Biological Process	GO:0007173	epidermal growth factor receptor signaling pathway	MGI:95294	IDA	Mouse	MGI:MGI:3032880\|PMID:14712229
Biological Process	GO:0007173	epidermal growth factor receptor signaling pathway	MGI:95294	IDA	Mouse	MGI:MGI:3531070\|PMID:15695332
Biological Process	GO:0007173	epidermal growth factor receptor signaling pathway	MGI:95294	IGI	Mouse	MGI:MGI:75839\|PMID:7641815
Biological Process	GO:0007173	epidermal growth factor receptor signaling pathway	P00533	IDA	Human	PMID:12435727
Biological Process	GO:0007173	epidermal growth factor receptor signaling pathway	RGD:2543	IDA	Rat	RGD:70386\|PMID:11796513
Biological Process	GO:0042698	menstrual cycle	RGD:2543	IMP	Rat	RGD:70386\|PMID:11796513
Biological Process	GO:0043066	negative regulation of apoptosis	RGD:2543	IMP	Rat	RGD:1581905\|PMID:16466740
Biological Process	GO:0045930	negative regulation of progression through mitotic cell cycle	RGD:2543	IMP	Rat	RGD:1581912\|PMID:14551192
Biological Process	GO:0048812	neurite morphogenesis	RGD:2543	IMP	Rat	RGD:1581898\|PMID:16648628
Biological Process	GO:0030335	positive regulation of cell migration	P00533	IMP	Human	PMID:12435727
Biological Process	GO:0008284	positive regulation of cell proliferation	MGI:95294	IGI	Mouse	MGI:MGI:75839\|PMID:7641815
Biological Process	GO:0008284	positive regulation of cell proliferation	MGI:95294	IDA	Mouse	MGI:MGI:3032880\|PMID:14712229
Biological Process	GO:0050679	positive regulation of epithelial cell proliferation	P00533	IDA	Human	PMID:10572067
Biological Process	GO:0043406	positive regulation of MAP kinase activity	P00533	IDA	Human	PMID:10572067
Biological Process	GO:0045429	positive regulation of nitric oxide biosynthetic process	P00533	IDA	Human	PMID:12828935
Biological Process	GO:0042327	positive regulation of phosphorylation	P00533	IDA	Human	PMID:15082764
Biological Process	GO:0048661	positive regulation of smooth muscle cell proliferation	RGD:2543	IMP	Rat	RGD:1581908\|PMID:15486316
Biological Process	GO:0051968	positive regulation of synaptic transmission, glutamatergic	RGD:2543	IMP	Rat	RGD:1581898\|PMID:16648628
Biological Process	GO:0046777	protein amino acid autophosphorylation	MGI:95294	IDA	Mouse	MGI:MGI:3054501\|PMID:15314156
Biological Process	GO:0007243	protein kinase cascade	RGD:2543	IDA	Rat	RGD:625656\|PMID:12107054
Biological Process	GO:0050999	regulation of nitric-oxide synthase activity	P00533	IDA	Human	PMID:12828935
Biological Process	GO:0050730	regulation of peptidyl-tyrosine phosphorylation	MGI:95294	IMP	Mouse	MGI:MGI:2182234\|PMID:11940581
Biological Process	GO:0050730	regulation of peptidyl-tyrosine phosphorylation	P00533	IMP	Human	PMID:12435727
Biological Process	GO:0051592	response to calcium ion	RGD:2543	IMP	Rat	RGD:1581907\|PMID:15950968
Biological Process	GO:0007165	signal transduction	MGI:95294	IDA	Mouse	MGI:MGI:2182234\|PMID:11940581
Biological Process	GO:0007165	signal transduction	RGD:2543	IDA	Rat	RGD:625656\|PMID:12107054
Biological Process	GO:0006412	translation	RGD:2543	IDA	Rat	RGD:625656\|PMID:12107054