Compare GO annotations for CHRNA7 and its OrthoDisease orthologs

Compare GO annotations for CHRNA7 and its orthologs

A table of the annotations represented in this image is provided below.

Annotations are indicated by colored nodes: mouse, human, rat, worm, fly, dicty, chicken, zfin, rice, tair, yeast, pombe, pfalc, and multiple.
Green arrows indicate "is_a"; Purple arrows indicate "part_of"
GO annotations: Mouse from MGI; Human from GO Annotations @ EBI (GOA); Rat from RGD; Chicken from GOA; Fly from FlyBase; Pfalc from PlasmoDB; Worm from WormBase; Dicty from dictyBase; Yeast from SGD; Zfin from ZFIN; Tair from TAIR/TIGR; Rice from Gramene; Pombe from Sanger GeneDB.
Does not include evidence codes: IEA, ISS, RCA, NR, ND, NAS, IC, IGC, TAS.
Graph is also available as SVG (requires viewer plug-in from Adobe)
All nodes are linked to the MGI GO browser.
Graph generated Fri Dec 7 09:49:59 2007.

Category	ID	Term	DB Object	Evidence	Organism	Reference
Molecular Function	GO:0042166	acetylcholine binding	RGD:2348	IMP	Rat	RGD:1600971\|PMID:16186249
Molecular Function	GO:0015464	acetylcholine receptor activity	P36544	IDA	Human	PMID:8906617
Molecular Function	GO:0008179	adenylate cyclase binding	RGD:2348	IPI	Rat	RGD:1600980\|PMID:12748066
Molecular Function	GO:0001540	beta-amyloid binding	P36544	IPI	Human	PMID:10681545
Molecular Function	GO:0017081	chloride channel regulator activity	P36544	IDA	Human	PMID:8145738
Molecular Function	GO:0008144	drug binding	RGD:2348	IDA	Rat	RGD:1600992\|PMID:15801858
Molecular Function	GO:0004889	nicotinic acetylcholine-activated cation-selective channel activity	MGI:99779	IMP	Mouse	MGI:MGI:85056\|PMID:9037516
Molecular Function	GO:0004889	nicotinic acetylcholine-activated cation-selective channel activity	MGI:99779	IMP	Mouse	MGI:MGI:1099674\|PMID:9364063
Molecular Function	GO:0004889	nicotinic acetylcholine-activated cation-selective channel activity	MGI:99779	IDA	Mouse	MGI:MGI:1202051\|PMID:9495872
Molecular Function	GO:0004889	nicotinic acetylcholine-activated cation-selective channel activity	MGI:99779	IMP	Mouse	MGI:MGI:2158987\|PMID:11834293
Molecular Function	GO:0004889	nicotinic acetylcholine-activated cation-selective channel activity	P36544	IDA	Human	PMID:8145738
Molecular Function	GO:0004889	nicotinic acetylcholine-activated cation-selective channel activity	P36544	IDA	Human	PMID:8906617
Molecular Function	GO:0004889	nicotinic acetylcholine-activated cation-selective channel activity	RGD:2348	IDA	Rat	RGD:727702\|PMID:12069582
Molecular Function	GO:0004889	nicotinic acetylcholine-activated cation-selective channel activity	RGD:2348	IDA	Rat	RGD:null
Molecular Function	GO:0004889	nicotinic acetylcholine-activated cation-selective channel activity	RGD:2348	IMP	Rat	RGD:null
Molecular Function	GO:0004889	nicotinic acetylcholine-activated cation-selective channel activity	RGD:2348	IMP	Rat	RGD:1600971\|PMID:16186249
Molecular Function	GO:0005515	protein binding	MGI:99779	IPI	Mouse	MGI:MGI:2176631\|PMID:11906696
Molecular Function	GO:0005515	protein binding	RGD:2348	IPI	Rat	RGD:null
Molecular Function	GO:0042803	protein homodimerization activity	P36544	IDA	Human	PMID:8145738
Molecular Function	GO:0015643	toxin binding	P36544	IDA	Human	PMID:12508119
Cellular Component	GO:0016324	apical plasma membrane	MGI:99779	IDA	Mouse	MGI:MGI:3603731\|PMID:16033766
Cellular Component	GO:0032279	asymmetric synapse	RGD:2348	IDA	Rat	RGD:1600985\|PMID:12077196
Cellular Component	GO:0030424	axon	RGD:2348	IDA	Rat	RGD:704420\|PMID:12645078
Cellular Component	GO:0030424	axon	RGD:2348	IDA	Rat	RGD:1600985\|PMID:12077196
Cellular Component	GO:0043025	cell soma	RGD:2348	IDA	Rat	RGD:704420\|PMID:12645078
Cellular Component	GO:0005737	cytoplasm	RGD:2348	IDA	Rat	RGD:1600985\|PMID:12077196
Cellular Component	GO:0043198	dendritic shaft	RGD:2348	IDA	Rat	RGD:1600985\|PMID:12077196
Cellular Component	GO:0043197	dendritic spine	RGD:2348	IDA	Rat	RGD:1600985\|PMID:12077196
Cellular Component	GO:0009897	external side of plasma membrane	MGI:99779	IDA	Mouse	MGI:MGI:3610855\|PMID:15963492
Cellular Component	GO:0030426	growth cone	RGD:2348	IDA	Rat	RGD:704420\|PMID:12645078
Cellular Component	GO:0045121	lipid raft	RGD:2348	IDA	Rat	RGD:1600980\|PMID:12748066
Cellular Component	GO:0005624	membrane fraction	MGI:99779	IDA	Mouse	MGI:MGI:2158987\|PMID:11834293
Cellular Component	GO:0005892	nicotinic acetylcholine-gated receptor-channel complex	P36544	IDA	Human	PMID:8906617
Cellular Component	GO:0005892	nicotinic acetylcholine-gated receptor-channel complex	RGD:2348	IDA	Rat	RGD:704420\|PMID:12645078
Cellular Component	GO:0005886	plasma membrane	P36544	IDA	Human	PMID:16280133
Cellular Component	GO:0005886	plasma membrane	RGD:2348	IDA	Rat	RGD:1600980\|PMID:12748066
Cellular Component	GO:0014069	postsynaptic density	RGD:2348	IDA	Rat	RGD:1600985\|PMID:12077196
Cellular Component	GO:0042734	presynaptic membrane	RGD:2348	IDA	Rat	RGD:1600985\|PMID:12077196
Biological Process	GO:0000187	activation of MAPK activity	P36544	IDA	Human	PMID:10771023
Biological Process	GO:0008306	associative learning	MGI:99779	IGI	Mouse	MGI:MGI:3513661\|PMID:15541879
Biological Process	GO:0008306	associative learning	MGI:99779	IMP	Mouse	MGI:MGI:3580035\|PMID:15922075
Biological Process	GO:0042113	B cell activation	MGI:99779	IMP	Mouse	MGI:MGI:3610855\|PMID:15963492
Biological Process	GO:0042113	B cell activation	MGI:99779	IMP	Mouse	MGI:MGI:3663537\|PMID:16253349
Biological Process	GO:0048149	behavioral response to ethanol	MGI:99779	IMP	Mouse	MGI:MGI:3511640\|PMID:15489024
Biological Process	GO:0035095	behavioral response to nicotine	MGI:99779	IGI	Mouse	MGI:MGI:3710706\|PMID:17470777
Biological Process	GO:0006816	calcium ion transport	P36544	IDA	Human	PMID:8145738
Biological Process	GO:0006816	calcium ion transport	P36544	IMP	Human	PMID:10771023
Biological Process	GO:0006816	calcium ion transport	RGD:2348	IMP	Rat	RGD:null
Biological Process	GO:0006874	cellular calcium ion homeostasis	P36544	IMP	Human	PMID:16280133
Biological Process	GO:0050890	cognition	P36544	IMP	Human	PMID:16754836
Biological Process	GO:0042416	dopamine biosynthetic process	RGD:2348	IEP	Rat	RGD:704388\|PMID:12438507
Biological Process	GO:0006897	endocytosis	MGI:99779	IMP	Mouse	MGI:MGI:3604036\|PMID:16025111
Biological Process	GO:0019228	generation of action potential	RGD:2348	IMP	Rat	RGD:1600975\|PMID:15044058
Biological Process	GO:0060112	generation of menstrual cycle rhythm	MGI:99779	IMP	Mouse	MGI:MGI:3053480\|PMID:15364017
Biological Process	GO:0006811	ion transport	MGI:99779	IMP	Mouse	MGI:MGI:1099674\|PMID:9364063
Biological Process	GO:0006811	ion transport	MGI:99779	IMP	Mouse	MGI:MGI:1355142\|PMID:10800961
Biological Process	GO:0007613	memory	MGI:99779	IMP	Mouse	MGI:MGI:3718964\|PMID:16923147
Biological Process	GO:0042698	menstrual cycle	MGI:99779	IMP	Mouse	MGI:MGI:3052645\|PMID:1400473
Biological Process	GO:0050728	negative regulation of inflammatory response	MGI:99779	IMP	Mouse	MGI:MGI:3721478\|PMID:16785311
Biological Process	GO:0050728	negative regulation of inflammatory response	P36544	IDA	Human	PMID:12508119
Biological Process	GO:0032691	negative regulation of interleukin-1 beta production	MGI:99779	IMP	Mouse	MGI:MGI:3040787\|PMID:12508119
Biological Process	GO:0032715	negative regulation of interleukin-6 production	MGI:99779	IMP	Mouse	MGI:MGI:3040787\|PMID:12508119
Biological Process	GO:0032720	negative regulation of tumor necrosis factor production	MGI:99779	IMP	Mouse	MGI:MGI:3040787\|PMID:12508119
Biological Process	GO:0032720	negative regulation of tumor necrosis factor production	MGI:99779	IMP	Mouse	MGI:MGI:3721478\|PMID:16785311
Biological Process	GO:0032720	negative regulation of tumor necrosis factor production	P36544	IMP	Human	PMID:12508119
Biological Process	GO:0045766	positive regulation of angiogenesis	P36544	IMP	Human	PMID:12189247
Biological Process	GO:0045766	positive regulation of angiogenesis	P36544	IMP	Human	PMID:16280133
Biological Process	GO:0008284	positive regulation of cell proliferation	P36544	IMP	Human	PMID:17498763
Biological Process	GO:0008284	positive regulation of cell proliferation	P36544	IMP	Human	PMID:16280133
Biological Process	GO:0001988	positive regulation of heart rate in baroreceptor response to decreased systemic arterial blood pressure	MGI:99779	IMP	Mouse	MGI:MGI:3531222\|PMID:10942027
Biological Process	GO:0050727	regulation of inflammatory response	MGI:99779	IMP	Mouse	MGI:MGI:3040787\|PMID:12508119
Biological Process	GO:0042391	regulation of membrane potential	MGI:99779	IMP	Mouse	MGI:MGI:1099674\|PMID:9364063
Biological Process	GO:0042391	regulation of membrane potential	MGI:99779	IMP	Mouse	MGI:MGI:1355142\|PMID:10800961
Biological Process	GO:0014061	regulation of norepinephrine secretion	MGI:99779	IMP	Mouse	MGI:MGI:3531222\|PMID:10942027
Biological Process	GO:0032225	regulation of synaptic transmission, dopaminergic	MGI:99779	IMP	Mouse	MGI:MGI:3716008\|PMID:16772172
Biological Process	GO:0045471	response to ethanol	MGI:99779	IMP	Mouse	MGI:MGI:3612839\|PMID:15555774
Biological Process	GO:0032094	response to food	MGI:99779	IMP	Mouse	MGI:MGI:3580035\|PMID:15922075
Biological Process	GO:0001666	response to hypoxia	P36544	IDA	Human	PMID:12189247
Biological Process	GO:0035094	response to nicotine	MGI:99779	IMP	Mouse	MGI:MGI:1202051\|PMID:9495872
Biological Process	GO:0035094	response to nicotine	MGI:99779	IMP	Mouse	MGI:MGI:3710894\|PMID:17291692
Biological Process	GO:0035094	response to nicotine	P36544	IDA	Human	PMID:12189247
Biological Process	GO:0035094	response to nicotine	P36544	IDA	Human	PMID:8145738
Biological Process	GO:0007165	signal transduction	P36544	IDA	Human	PMID:8906617
Biological Process	GO:0030317	sperm motility	MGI:99779	IMP	Mouse	MGI:MGI:3691713\|PMID:15944242
Biological Process	GO:0007271	synaptic transmission, cholinergic	MGI:99779	IMP	Mouse	MGI:MGI:1099674\|PMID:9364063
Biological Process	GO:0007271	synaptic transmission, cholinergic	RGD:2348	IMP	Rat	RGD:1600975\|PMID:15044058
Biological Process	GO:0042110	T cell activation	MGI:99779	IMP	Mouse	MGI:MGI:3663537\|PMID:16253349