Compare GO annotations for BCL2 and its OrthoDisease orthologs

Compare GO annotations for BCL2 and its orthologs

A table of the annotations represented in this image is provided below.

Annotations are indicated by colored nodes: mouse, human, rat, worm, fly, dicty, chicken, zfin, rice, tair, yeast, pombe, pfalc, and multiple.
Green arrows indicate "is_a"; Purple arrows indicate "part_of"
GO annotations: Mouse from MGI; Human from GO Annotations @ EBI (GOA); Rat from RGD; Chicken from GOA; Fly from FlyBase; Pfalc from PlasmoDB; Worm from WormBase; Dicty from dictyBase; Yeast from SGD; Zfin from ZFIN; Tair from TAIR/TIGR; Rice from Gramene; Pombe from Sanger GeneDB.
Does not include evidence codes: IEA, ISS, RCA, NR, ND, NAS, IC, IGC, TAS.
Graph is also available as SVG (requires viewer plug-in from Adobe)
All nodes are linked to the MGI GO browser.
Graph generated Fri Dec 7 09:49:59 2007.

Category	ID	Term	DB Object	Evidence	Organism	Reference
Molecular Function	GO:0051434	BH3 domain binding	P10415	IPI	Human	PMID:9111042
Molecular Function	GO:0002020	protease binding	P10415	IDA	Human	PMID:10620603
Molecular Function	GO:0005515	protein binding	MGI:88138	IPI	Mouse	MGI:MGI:3709531\|PMID:17274640
Molecular Function	GO:0005515	protein binding	RGD:2199	IPI	Rat	RGD:1581919\|PMID:15004018
Molecular Function	GO:0046982	protein heterodimerization activity	MGI:88138	IPI	Mouse	MGI:MGI:1931634\|PMID:11226327
Molecular Function	GO:0046982	protein heterodimerization activity	P10415	IPI	Human	PMID:9111042
Molecular Function	GO:0042803	protein homodimerization activity	P10415	IDA	Human	PMID:9111042
Cellular Component	GO:0005737	cytoplasm	P10415	IDA	Human	PMID:11530860
Cellular Component	GO:0005737	cytoplasm	RGD:2199	IDA	Rat	RGD:1581915\|PMID:15341589
Cellular Component	GO:0005829	cytosol	MGI:88138	IDA	Mouse	MGI:MGI:2385392\|PMID:12050152
Cellular Component	GO:0005829	cytosol	MGI:88138	IDA	Mouse	MGI:MGI:2683362\|PMID:14551195
Cellular Component	GO:0005741	mitochondrial outer membrane	P10415	IDA	Human	PMID:9027314
Cellular Component	GO:0005739	mitochondrion	MGI:88138	IDA	Mouse	MGI:MGI:2445910\|PMID:12420306
Cellular Component	GO:0005739	mitochondrion	MGI:88138	IDA	Mouse	MGI:MGI:2682130\|PMID:14651853
Cellular Component	GO:0005739	mitochondrion	P10415	IDA	Human	PMID:9027314
Cellular Component	GO:0005739	mitochondrion	RGD:2199	IDA	Rat	RGD:1581915\|PMID:15341589
Cellular Component	GO:0031965	nuclear membrane	P10415	IDA	Human	PMID:1502141
Biological Process	GO:0006916	anti-apoptosis	MGI:88138	IDA	Mouse	MGI:MGI:1203837\|PMID:9560217
Biological Process	GO:0006916	anti-apoptosis	MGI:88138	IDA	Mouse	MGI:MGI:2683362\|PMID:14551195
Biological Process	GO:0006916	anti-apoptosis	MGI:88138	IGI	Mouse	MGI:MGI:2179928\|PMID:12082633
Biological Process	GO:0006916	anti-apoptosis	P10415	IDA	Human	PMID:10506221
Biological Process	GO:0006916	anti-apoptosis	P10415	IDA	Human	PMID:11684014
Biological Process	GO:0006916	anti-apoptosis	P10415	IDA	Human	PMID:9027314
Biological Process	GO:0006916	anti-apoptosis	P10415	IDA	Human	PMID:10620603
Biological Process	GO:0006916	anti-apoptosis	RGD:2199	IDA	Rat	RGD:70671\|PMID:11879647
Biological Process	GO:0006916	anti-apoptosis	RGD:2199	IMP	Rat	RGD:1581919\|PMID:15004018
Biological Process	GO:0006915	apoptosis	MGI:88138	IDA	Mouse	MGI:MGI:67275\|PMID:8358790
Biological Process	GO:0051607	defense response to virus	P10415	IDA	Human	PMID:10620603
Biological Process	GO:0031069	hair follicle morphogenesis	MGI:88138	IMP	Mouse	MGI:MGI:63353\|PMID:8402909
Biological Process	GO:0043066	negative regulation of apoptosis	MGI:88138	IDA	Mouse	MGI:MGI:3584078\|PMID:15983387
Biological Process	GO:0043066	negative regulation of apoptosis	MGI:88138	IDA	Mouse	MGI:MGI:2686748\|PMID:14707049
Biological Process	GO:0032848	negative regulation of cellular pH reduction	P10415	IDA	Human	PMID:10506221
Biological Process	GO:0043524	negative regulation of neuron apoptosis	MGI:88138	IDA	Mouse	MGI:MGI:79659\|PMID:8625820
Biological Process	GO:0043473	pigmentation	MGI:88138	IMP	Mouse	MGI:MGI:63353\|PMID:8402909
Biological Process	GO:0008284	positive regulation of cell proliferation	MGI:88138	IDA	Mouse	MGI:MGI:2179155\|PMID:11983915
Biological Process	GO:0046902	regulation of mitochondrial membrane permeability	MGI:88138	IDA	Mouse	MGI:MGI:3700463\|PMID:9843949
Biological Process	GO:0051881	regulation of mitochondrial membrane potential	MGI:88138	IDA	Mouse	MGI:MGI:3700463\|PMID:9843949
Biological Process	GO:0000074	regulation of progression through cell cycle	P10415	IDA	Human	PMID:10848600
Biological Process	GO:0043497	regulation of protein heterodimerization activity	P10415	IDA	Human	PMID:9111042
Biological Process	GO:0043496	regulation of protein homodimerization activity	P10415	IDA	Human	PMID:9111042
Biological Process	GO:0045069	regulation of viral genome replication	MGI:88138	IDA	Mouse	MGI:MGI:3700400\|PMID:16950491
Biological Process	GO:0001836	release of cytochrome c from mitochondria	MGI:88138	IDA	Mouse	MGI:MGI:3700463\|PMID:9843949
Biological Process	GO:0031000	response to caffeine	RGD:2199	IEP	Rat	RGD:1599474\|PMID:17236787
Biological Process	GO:0043627	response to estrogen stimulus	RGD:2199	IEP	Rat	RGD:1599488\|PMID:16084662
Biological Process	GO:0045471	response to ethanol	RGD:2199	IEP	Rat	RGD:1599492\|PMID:15469889
Biological Process	GO:0009408	response to heat	RGD:2199	IEP	Rat	RGD:1599475\|PMID:17131910
Biological Process	GO:0001666	response to hypoxia	RGD:2199	IEP	Rat	RGD:1599476\|PMID:16445580
Biological Process	GO:0010035	response to inorganic substance	RGD:2199	IEP	Rat	RGD:1599485\|PMID:16256253
Biological Process	GO:0010039	response to iron ion	P10415	IDA	Human	PMID:11264898
Biological Process	GO:0035094	response to nicotine	P10415	IDA	Human	PMID:12421819
Biological Process	GO:0035094	response to nicotine	RGD:2199	IEP	Rat	RGD:1599493\|PMID:15332118
Biological Process	GO:0007584	response to nutrient	RGD:2199	IEP	Rat	RGD:1599487\|PMID:16216918
Biological Process	GO:0010033	response to organic substance	RGD:2199	IEP	Rat	RGD:1599486\|PMID:16249675
Biological Process	GO:0043434	response to peptide hormone stimulus	RGD:2199	IEP	Rat	RGD:1599489\|PMID:15686664
Biological Process	GO:0009636	response to toxin	P10415	IDA	Human	PMID:16307838