Compare GO annotations for ALAS2 and its OrthoDisease orthologs

Compare GO annotations for ALAS2 and its orthologs

A table of the annotations represented in this image is provided below.

Annotations are indicated by colored nodes: mouse, human, rat, worm, fly, dicty, chicken, zfin, rice, tair, yeast, pombe, pfalc, and multiple.
Green arrows indicate "is_a"; Purple arrows indicate "part_of"
GO annotations: Mouse from MGI; Human from GO Annotations @ EBI (GOA); Rat from RGD; Chicken from GOA; Fly from FlyBase; Pfalc from PlasmoDB; Worm from WormBase; Dicty from dictyBase; Yeast from SGD; Zfin from ZFIN; Tair from TAIR/TIGR; Rice from Gramene; Pombe from Sanger GeneDB.
Does not include evidence codes: IEA, ISS, RCA, NR, ND, NAS, IC, IGC, TAS.
Graph is also available as SVG (requires viewer plug-in from Adobe)
All nodes are linked to the MGI GO browser.
Graph generated Fri Dec 7 09:49:59 2007.

Category	ID	Term	DB Object	Evidence	Organism	Reference
Molecular Function	GO:0003870	5-aminolevulinate synthase activity	P22557	IDA	Human	PMID:14643893
Molecular Function	GO:0003870	5-aminolevulinate synthase activity	RGD:2084	IDA	Rat	RGD:632181\|PMID:8407861
Molecular Function	GO:0003870	5-aminolevulinate synthase activity	RGD:2084	IDA	Rat	RGD:1581096\|PMID:15181459
Molecular Function	GO:0003870	5-aminolevulinate synthase activity	S000002640	IMP	Yeast	SGD_REF:S000057328\|PMID:7035824
Molecular Function	GO:0050662	coenzyme binding	RGD:2084	IDA	Rat	RGD:632181\|PMID:8407861
Molecular Function	GO:0016594	glycine binding	RGD:2084	IDA	Rat	RGD:632181\|PMID:8407861
Molecular Function	GO:0005515	protein binding	P22557	IPI	Human	PMID:14643893
Molecular Function	GO:0005515	protein binding	P22557	IPI	Human	PMID:10727444
Molecular Function	GO:0005515	protein binding	P22557	IPI	Human	PMID:16234850
Cellular Component	GO:0005743	mitochondrial inner membrane	P22557	IDA	Human	PMID:14643893
Cellular Component	GO:0005759	mitochondrial matrix	S000002640	IDA	Yeast	SGD_REF:S000054004\|PMID:3023841
Cellular Component	GO:0005739	mitochondrion	P22557	IDA	Human	PMID:10727444
Cellular Component	GO:0005739	mitochondrion	RGD:2084	IDA	Rat	RGD:15496594
Cellular Component	GO:0005739	mitochondrion	RGD:2084	IDA	Rat	RGD:1581087\|PMID:15496594
Cellular Component	GO:0005739	mitochondrion	S000002640	IDA	Yeast	SGD_REF:S000117178\|PMID:16823961
Cellular Component	GO:0005625	soluble fraction	RGD:2084	IDA	Rat	RGD:15496594
Biological Process	GO:0006783	heme biosynthetic process	S000002640	IMP	Yeast	SGD_REF:S000057328\|PMID:7035824
Biological Process	GO:0045449	regulation of transcription	S000002640	IMP	Yeast	SGD_REF:S000074341\|PMID:12928433
Biological Process	GO:0001666	response to hypoxia	P22557	IDA	Human	PMID:16234850
Biological Process	GO:0001666	response to hypoxia	RGD:2084	IEP	Rat	RGD:1599040\|PMID:17095594